Metastatic Pancreatic Cancer Clinical Trial
Official title:
A Phase II, Single-arm Study to Evaluate the Efficacy and Safety of the Combination of Nab-paclitaxel and Gemcitabine in Treating Patients With Metastatic Pancreatic Cancer
This is a single arm, open-label Phase II clinical trial to Evaluate the Efficacy and Safety of the Combination of Nab-paclitaxel and Gemcitabine in Treating Patients with metastatic pancreatic cancer.
While GT (Gemcitabine + Nab-paclitaxel) is one of the preferred regimens for metastatic
pancreatic cancer, we have yet to determine the optimum number of cycles for GT treatment
regimen. In this single arm, open-label clinical trial, metastatic pancreatic cancer patients
will be received nab-paclitaxel 100 mg/m^2 (iv, 30 minutes) and gemcitabine 1000 mg/m^2 for 3
weeks, followed by one week without treatment. Treatment repeats every 4 weeks until the
disease recurrence or unacceptable toxicity, death or begin a novel therapeutic.
The safety and efficacy of each group will be assessed through ORR, PFS, OS and adverse
effects as graded by CTC-AE 5.0.
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