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Clinical Trial Summary

The primary objective of this study is to determine the progression-free survival (PFS) of participants with previously untreated metastatic malignant melanoma when treated with IMC-1121B (ramucirumab) alone or in combination with dacarbazine.


Clinical Trial Description

The purpose of this study is to determine the antitumor activity and safety profile of IMC-1121B (ramucirumab) when used alone or in combination with dacarbazine in participants with metastatic melanoma who have not received prior chemotherapy for this disease. ;


Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment


Related Conditions & MeSH terms


NCT number NCT00533702
Study type Interventional
Source Eli Lilly and Company
Contact
Status Completed
Phase Phase 2
Start date November 2007
Completion date May 2011

See also
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Terminated NCT01705392 - Bevacizumab vs Dacarbazine in Metastatic Melanoma Phase 2
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Terminated NCT00961844 - Trial for Vaccine Therapy With Dendritic Cells in Patients With Metastatic Malignant Melanoma Phase 1/Phase 2
Completed NCT00462423 - Abraxane and Avastin as Therapy for Patients With Malignant Melanoma, a Phase II Study Phase 2