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Prospective Tumor Response Evaluation — Liver  

Hepatocellular Cancer Clinical Trial

Official title:
Prospective Evaluation of Tumor Response to Cancer Treatment Therapies

Clinical Trial Summary

The purpose of this study is to determine if MRI imaging can detect genetic, proteomic, and metabolomic characteristics of liver tumors. The study also aims to determine if these imaging characteristics are correlated with clinical outcomes.

Clinical Trial Description

For each treatment arm, pre-procedural MRI and post procedural MRI will be obtained. Pre-procedural biopsies will be obtained, if possible. Pretreatment genetic expression, proteomic, or metabolomic patterns from the tumor samples will be assessed. Imaging characteristics from tumors will be extracted using automated software—the study will apply a computational analysis system with the capability to extract and analyze imaging characteristics and correlate them to genetic expression, proteomic, and metabolomic tumor characteristics. Imaging findings will be correlated to clinical outcomes and genetic, proteomic, and metabolomic findings to determine association. Imaging findings and genomic, proteomic, and metabolomic tumor characteristics will be correlated to clinical outcomes (time to recurrence, overall survival, 3-month, 6-month, and 1-year survival). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02787954
Study type Observational [Patient Registry]
Source The University of Texas Health Science Center, Houston
Contact
Status Terminated
Phase
Start date January 2016
Completion date April 2017
View Details
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