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Clinical Trial Summary

This was a phase Ib study of PDR001 in combination with bevacizumab and mFOLFOX6 as first line therapy in patients with metastatic microsatellite stable (MSS) colorectal cancer. The study was to have assessed primarily, the safety and tolerability and then the efficacy of PDR001 in combination with bevacizumab and mFOLFOX6. Particular attention would have been paid to the level of activity of study drug combinations in CMS4 patients (retrospective analysis). The study was terminated early due to company decision.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03176264
Study type Interventional
Source Novartis
Contact
Status Terminated
Phase Phase 1
Start date September 25, 2017
Completion date January 30, 2018

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