Metastatic Colorectal Cancer Clinical Trial
Official title:
A Retrospective Review of Liver Resection Rate in Metastatic Colorectal Cancer Patients Following Downsizing Treatment With Chemotherapy Plus Cetuximab in Normal UK National Health Service Clinical Practice
This study is a multi-centre retrospective observational research study which will be
conducted in UK centres with specialised liver surgical services.
The study will involve retrospective review of medical records of patients with metastatic
colorectal cancer (mCRC) with metastases confined to the liver, defined locally as
unresectable without downsizing therapy at first review by a Hepatobiliary Multi
Disciplinary Team (HPB MDT). Erbitux is available for use in combination with chemotherapy
as a downsizing treatment for patients with previously unresectable metastases.
The study aims to examine liver resection rates achieved in normal clinical practice in
order to inform National Health Service (NHS) clinical and policy decision making and to
further understanding of how cetuximab is used in a standard clinical setting. This study
intends to estimate the proportion of patients with unresectable liver metastases who
undergo liver resection following downsizing treatment with chemotherapy plus cetuximab.
n/a
Time Perspective: Retrospective
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