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Metallic Taste clinical trials

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NCT ID: NCT03558789 Completed - Metallic Taste Clinical Trials

Metallic Taste Before, During and After Treatment of Head and Neck Cancer

TORCAD
Start date: April 26, 2018
Phase:
Study type: Observational

Metallic taste in head and neck cancer is widely under-estimated in the literature. Its causes are multiple and poorly defined. Though it has a strong impact on the nutritional status. The main objective of the TORCAD project is to test the hypothesis that intraoral lipoperoxidation is associated to metallic taste onset before, during and after treatment of head and neck cancer (HNC). The secondary goals are to evaluate the involvement of others physiopathological factors in metallic taste: (i) additional chemical modification in the saliva; (ii) release of inhibition of the facial nerve on the glossopharyngeal nerve; presence of an intraoral electric current; food pleasantness and acceptability; quality of life.