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Metabolic Syndrome clinical trials

View clinical trials related to Metabolic Syndrome.

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NCT ID: NCT05845424 Not yet recruiting - Metabolic Syndrome Clinical Trials

High-intensity Statin and Ezetimibe Therapy for Asymptomatic Patients With Positive Coronary Calcium

DECISION-CAL
Start date: June 1, 2023
Phase: Phase 4
Study type: Interventional

The aim of this study is to compare safety and efficacy between the aggressive treatment with combination of high-intensity statin and ezetimibe and the current standard lipid lowering treatment in asymptomatic patients with presence of coronary calcification.

NCT ID: NCT05843682 Active, not recruiting - Clinical trials for Essential Hypertension

Technological Innovation in the Virtual Assistance of Patients With Uncontrolled Arterial Hypertension - Hyper 2

Hyper2
Start date: October 7, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the effectiveness of the use of artificial intelligence in home monitoring in patients with uncontrolled arterial hypertension.

NCT ID: NCT05843162 Not yet recruiting - Metabolic Syndrome Clinical Trials

A Clinical Trial to Evaluate the Blood Pressure Control of Telmisartan or Losartan in Essential Hypertensive Patients With Metabolic Syndrome

PRISTINE
Start date: June 1, 2023
Phase: Phase 4
Study type: Interventional

This is a multi-center, randomized, open-label, active comparator-controlled, phase 4 clinical trial to evaluate the blood pressure control of Telmisartan or Losartan in essential hypertensive patients with metabolic syndrome

NCT ID: NCT05842811 Not yet recruiting - Metabolic Syndrome Clinical Trials

An Observational Study of Patients With Metabolic Syndrome and Related Conditions

Start date: May 24, 2023
Phase:
Study type: Observational

TARGET-METABOLIC is an observational research study to conduct a comprehensive review of outcomes for patients with metabolic syndrome and related conditions.

NCT ID: NCT05839444 Completed - Metabolic Syndrome Clinical Trials

A Clinical Study to Evaluate the Safety and Tolerability of BioPB-01 in Healthy Adults

Start date: April 27, 2023
Phase: N/A
Study type: Interventional

The present study is a randomized, placebo-controlled, parallel-group, double-blind clinical study. Seventy-eight individuals will be screened, and considering a screening failure rate of 20%, approximately 64 participants will be randomized in a ratio of 1:1 to receive either BioPB-01 or Placebo

NCT ID: NCT05834309 Recruiting - Metabolic Syndrome Clinical Trials

Exercise Effects on Health Status in Patients With Severe Mental Illness

SMI01
Start date: December 5, 2022
Phase: N/A
Study type: Interventional

People with severe mental disorders have a mortality rate 2 to 3 times higher than that of the general population, largely due to the presence of comorbidities, with a predominance of cardiovascular disease. This population has a higher risk of developing metabolic syndrome compared to the healthy population. Several factors are involved. The usual pharmacological treatment in people with severe mental disorder is a risk factor for the development of metabolic syndrome and deterioration of physical condition. This is generally compounded by poor health care, high-calorie diets, a sedentary lifestyle, difficulties in coping with life situations that generate emotional states (anxiety and/or depression) that result in unhealthy lifestyle habits related to food, activity, interpersonal relationships, sleep, consumption habits (tobacco, alcohol and drugs) and other environmental factors. Physical exercise has been proposed as one of the most effective treatments to reverse the negative consequences of low levels of physical activity in this population. However, the mechanism of action of exercise on health status and the optimal "dose" and intensity of exercise to achieve the greatest number of benefits with respect to cardiometabolic health in patients with severe mental disorder are unknown.The study will be carried out at the Mental Health Rehabilitation Unit of Navarra, a center under the Mental Health Management of Osasunbidea, where people between 18 and 65 years of age with a diagnosis of severe mental illness in a situation of clinical stability receive treatment.The sample will be composed of 100 participants from consecutive admissions to the Rehabilitation Unit. The subjects will be randomized into 2 groups; a control group that will receive the usual specialized care and an intervention group, which in addition to receiving the usual rehabilitation treatment, will undergo a 6-week multicomponent physical exercise program performed 2 days per week. The effects of exercise on the inflammatory profile, metabolic parameters, physical condition, cognitive function, vascular function, muscle strength, health-related quality of life, lifestyle habits (diet, activation, sleep, substance use) and mood will be evaluated.

NCT ID: NCT05832190 Recruiting - Metabolic Syndrome Clinical Trials

Correcting GUT microbioTa by Combined Supplementation of fibERs and bIotiN to Improve Microbiome and Optimize Bariatric Surgery Outcomes

GUTERRING
Start date: July 24, 2023
Phase: N/A
Study type: Interventional

Bariatric surgery improves health outcomes with a maximal weight loss on average occurring 1 year after surgery but with dramatic between-subjects variability in weight loss (ranging from 20 to 160% excess weight loss) for reasons that remain to be elucidated. The investigators hypothesize that targeting the 3 months pre-surgery period by a calibrated dietary intervention, with fiber enrichment and biotin, will improve gut microbiota richness and subsequently improve subjects' metabolic health that may optimize post bariatric surgery outcomes. The study is designed as a pilot, comparative, randomized, open-label trial with 4 arms: standard of care, biotin only, fibers only, biotin + fibers.

NCT ID: NCT05830552 Completed - Metabolic Syndrome Clinical Trials

The Effect of Feedback on Physical Activity Surveillance Using Wearable Device-Smartphone Application for Resolution of Metabolic Syndrome in Aged 60 or Older

Start date: November 1, 2021
Phase: N/A
Study type: Interventional

The Effect of Feedback on Physical Activity Surveillance using Wearable Device-Smartphone Application for Resolution of Metabolic Syndrome in Aged 60 or older; a 12-Week Randomized Control Study

NCT ID: NCT05811923 Completed - Metabolic Syndrome Clinical Trials

Changes in Metabolic Rate and Perceptual Indicators After Acute Ingestion of Paraxanthine

PX
Start date: December 12, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the acute impact of ingesting individual and combined dosages of caffeine and paraxanthine in comparison to placebo on changes in resting metabolic rate, perceived levels of affect, and markers of lipolysis.

NCT ID: NCT05808192 Completed - Single Transplant Clinical Trials

De Novo Metabolic Syndrome in Liver Transplant Patients After Immunosuppression Withdrawal

Start date: September 1, 2020
Phase:
Study type: Observational

Evaluate de novo onset of metabolic syndrome, NAFLD and NASH in liver transplant recipients who have discontinued immunosuppressive therapy ("tolerant") and in those taking immunosuppressive therapy ("non-tolerant").