Metabolic Bone Disorder Clinical Trial
Official title:
Investigations of the Effect of MK-7 on Bone and Glucose Metabolism and Arterial Calcification
The aims of the present study are to investigate the effect of vitamin K2 on bone turnover,
bone mass, bone structure, glucose metabolism, and arteriosclerosis.
Osteoporosis, diabetes, metabolic syndrome and cardiovascular disease are common diseases
that affect large groups of people in the Western world.
Our hypotheses is that vitamin K2 (MK-7) reduces undercarboxylated osteocalcin in
postmenopausal women and reduces bone turnover and increases bone mineral density; increases
insulin sensitivity and decreases indices of arterial calcification.
Osteoporosis, diabetes, metabolic syndrome and cardiovascular disease are common diseases
that affect large groups of people in the Western world.
Our hypotheses is that vitamin K2 (MK-7) reduces undercarboxylated osteocalcin in
postmenopausal women and reduces bone turnover and increases bone mineral density; increases
insulin sensitivity and decreases indices of arterial calcification.
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Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Prevention