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Ga-68 FAPI PET Before Immunotherapy — FAPBI  

Mesotheliomas Pleural Clinical Trial

Official title:
Prognostic Significance of Ga-68 FAPI PET Before Immunotherapy in Pleural Mesothelioma

Clinical Trial Summary

It is aimed to evaluate FAP expression and its success in predicting treatment response before immunotherapy used in the treatment of malignant mesothelioma with Ga68 FAPI PET/CT imaging, which allows in vivo evaluation of FAP expression, which is thought to be associated with immunosuppression and resistance to immunotherapy.

Clinical Trial Description

Patients diagnosed with pleural mesothelioma and planned for immunotherapy will be included in the study. Patients will undergo Ga68 FAPI PET/CT imaging within 10 days before the start of immunotherapy treatment, and SUVmax, SUVmean, metabolic tumor volume and total Ga68 FAPI uptake parameters will be obtained from the tumors. Following this, the routine treatment and follow-up of the patients will be carried out by their clinicians. It will be evaluated whether there is a correlation between treatment response and initial Ga-68 FAPI PET findings. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06451536
Study type Interventional
Source Ankara University
Contact
Status Recruiting
Phase N/A
Start date April 30, 2024
Completion date April 30, 2025
View Details
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