Serum Lactate in Acute Mesenteric Ischemia

Mesenteric Ischemia Clinical Trial

Official title: Lactate Dehydrogenase, Bowel Necrosis and Mortality in Acute Mesenteric Ischemia: Retrospective Cross-Sectional

Status Completed

Clinical Trial Summary

Background: Acute mesenteric ischemia is a vascular emergency with high mortality because of ambiguous symptomatology and a lack of early diagnostic markers. Lactate dehydrogenase has been described as a mortality biomarker and bowel necrosis length too. Nevertheless, the association between them has been mildly studied. Our objective was to evaluate the association between serum lactate admission levels, bowel necrosis extension, and mortality. Additionally, we performed a mortality characterization. Materials and Methods: A retrospective cross-sectional study was designed. We reviewed patients' clinical records with acute mesenteric ischemia that attended a hospital between 2012 and 2018. We compared serum lactate admission levels with bowel necrosis length and mortality. A receiver operating characteristic curve was performed on the last association. As post hoc analysis, a classification and regression tree on mortality was fitted.

Clinical Trial Description

n/a

Related Conditions & MeSH terms

• Ischemia
• Mesenteric Ischemia

• NCT number: NCT04671979
• Study type: Observational [Patient Registry]
• Source: Universidad del Rosario
• Status: Completed
• Start date: May 2, 2017
• Completion date: June 30, 2020