Mesenchymal Tumor Clinical Trial
Official title:
High-Dose Proton/Photon RT + Surgery of Sarcomas of the Thoracic, Lumbar Spine/Sacrum
The purpose of this study is to test the effectiveness of high dose radiation administered by both proton and photon therapy. Radiation is an effective treatment for many types of tumors and it is thought that radiation alone, when given in much higher doses over a shorter period of time, may be more effective in controlling recurrence of sarcoma.
- In this study three types of radiation will be used: standard radiation (called
photon); alternative form of radiation called proton beam therapy; and a localized
radiation applicator plaque that can be applied to the surface of the dura (the fibrous
outer envelope that surrounds the spinal cord and fluid surrounding the spinal cord) at
time of surgical removal of the tumor.
- Radiation treatments (photon and proton) and possibly surgical removal of portions of
the tumor with intraoperative radiation delivery to the surface dura with
intraoperative radiation delivery will be performed over a period of 12 weeks. As part
of the treatment planning process, participants will need two treatment planning CT
scans and 2-3 treatment planning sessions.
- Participants will receive, in total, 39-43 photon/proton treatments.
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