Meralgia Paresthetica Clinical Trial
Official title:
Efficacy of Neural Prolotherapy in Treatment of Meralgia Paresthetica
Meralgia paresthetica is an entrapment neuropathy of the lateral femoral cutaneous nerve. Its
main manifestation is neuropathic pain on the lateral aspect of the thigh. Neural
prolotherapy has shown improvement and relieve of neuropathic pain.
The aim of the current study was to assess the efficacy of neural prolotherapy (subcutaneous
perineural injection of dextrose 5% solution) on reliving pain and improvement of function
and quality of life in patients with meralgia paresthetica.
Meralgia paresthetica is a mononeuropathy of the lateral femoral cutaneous nerve (i.e.
lateral cutaneous nerve of the thigh). It is known as the lateral cutaneous nerve of the
thigh neuralgia. It is due to a lot of etiologies. It is characterized by neuropathic pain,
tingling, paresthesia and numbness in the anterolateral aspect of the thigh. The symptoms may
be provoked or worsened by prolonged standing and walking. Sitting may alleviate the pain
because there is reduction of the tension over the nerve, The treatment of meralgia
paresthetica is directed towards the improvement of the symptoms which is mainly pain with
subsequent improvement of function and quality of life, as well as, treatment of the
etiology. The treatment includes conservative and surgical treatment. Conservative treatment
consists of non-pharmacologic treatment and pharmacologic treatment. Surgical treatment takes
place in case of failure of the conservative treatment. Surgical options consist of
neurolysis and neurectomy.
Neural prolotherapy was reported to improve and relieve of neuropathic pain including that of
meralgia paresthetica. Neural prolotherapy is the subcutaneous perineural injection of
isotonic dextrose (5%) solution especially at the points of fascial penetration of the
sensory nerve. It is the site where the sensory nerve reaches the subcutaneous plane. There
are scanty studies assessed this issue.
The aim of the current study was to assess the efficacy of neural prolotherapy (subcutaneous
perineural injection of dextrose 5% solution) on reliving pain and improvement of function
and quality of life in patients with meralgia paresthetica.
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