Investigation of Female Reproductive Hormone Dynamics During Adolescence

Status Completed

Clinical Trial Summary

Irregular menstrual cycles are common in girls for several years after their first menstrual period. The cause of abnormal menstrual cycles during this time is not well-understood. The purpose of this study is to: 1) monitor girls during a menstrual cycle (with blood and urine sampling and serial pelvic ultrasounds) to identify those girls who do not ovulate (release of an egg from the ovary), and 2) determine whether cycles can be corrected by treating girls with a short course of low-dose estrogen and progesterone.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Menstruation Disturbances

Clinical Trial Details

NCT number	NCT02486757
Study type	Interventional
Source	Massachusetts General Hospital
Contact
Status	Completed
Phase	Early Phase 1
Start date	April 2015
Completion date	March 1, 2016

View Details

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