Clinical Trials Logo
  1. Home
  2. Menstrual Irregularity
  3. NCT05230316

Gynecological Symptoms and Health-related Quality of Life in Egyptian Women With SLE

SLE Clinical Trial

Official title:
Recognizing Gynecological Symptoms and Health-related Quality of Life in Egyptian Women With Systemic Lupus Erythematosus

Clinical Trial Summary

The purpose of our study was to Recognize gynecological symptoms and health-related quality of life in Egyptian women with systemic lupus erythematosus and evaluate the impact of duration of remission on QOL in SLE patients.

Clinical Trial Description

Despite significant advances in recent decades, systemic lupus erythematosus (SLE) is still burdened by irreversible organ damage and a notable impact on health-related quality of life (HRQoL). Improving the quality of life is a pivotal goal in the management of SLE. According to the Treat to Target (T2T) recommendations for SLE management, particular attention needs to be paid to the factors that negatively influence HRQoL such as fatigue, pain and depression. Recent epidemiological studies demonstrate that prolonged remission is an achievable target in SLE patients and is clearly associated with better outcomes in terms of damage accrual. Such findings also raise questions about the possible impact of remission on HRQoL. In a retrospective study, Patients in prolonged remission reported significantly better HRQoL as assessed by the 36-Item Short-Form Health Survey (SF36) and Lupus PRO questionnaire. Methodology in details L: 70 women with SLE will be included in this study from the outpatient clinic. in Fayoum University hospital It will be conducted in the Department of Obstetrics and Gynecology, Fayoum University Maternity Hospital, Egypt. Full history taking (Age, Duration of marriage, Parity, Occupation, Mode of delivery, History of abortion, Medical and Surgical history). Menstrual histories obtained from participants included: age at menarche, duration of heavy bleeding, duration of menses and menstrual cycle, and other gynecological symptoms as Questionnaire form. Patients' blood pressure, height, weight, body mass index (BMI), and other clinical parameters were reviewed by the attending doctors. The patient's medications, which included immunosuppressive therapy such as steroids, cyclophosphamide, azathioprine, and cyclosporine A, where noted, and the use of other adjunctive medications were also recorded. Definition of remission Definition of remission was in line with European Consensus Criteria . Clinical remission (CLR) was present when clinical SLEDAI score=0 and physician global score less than 0.5 ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05230316
Study type Observational
Source Fayoum University
Contact
Status Active, not recruiting
Phase
Start date January 15, 2022
Completion date August 2023
View Details
See also
  Status Clinical Trial Phase
Not yet recruiting NCT05479071 - Relation of Antibodies Against Oxidized Low Density Lipoproteins to Disease Activity and Cardiovascular Affection in Systemic Lupus.
Completed NCT02240888 - Vaccination in Inflammatory Rheumatic Disease (VACCIMIL). The Impact of Antirheumatic Treatment on Antibody Response N/A
Active, not recruiting NCT05748925 - Cardio Renal Effects of SGLT2 Inhibitors Among Lupus Nephritis Patients Phase 4
Not yet recruiting NCT04517240 - A Study on Protein Losing Enteropathy In Systemic Lupus Erythematosus
Completed NCT00710021 - Vitamin D3 in Systemic Lupus Erythematosus Phase 2
Terminated NCT01946880 - Randomized MMF Withdrawal in Systemic Lupus Erythematosus (SLE) Phase 2
Recruiting NCT06445127 - Evaluation of Patients With Lupus Nephritis Using Kidney MRI (Magnetic Resonance Imaging) N/A
Active, not recruiting NCT04018222 - Translation of a Diagnostic Test for Lupus Flare Prediction From Bench to Clinic
Completed NCT03240536 - Choosing Tests Wisely in Rheumatology N/A
Completed NCT04368299 - Telemedicine for Follow-up of Systemic Lupus Erythematosus N/A
Active, not recruiting NCT04037293 - Premature Atherosclerosis in Systemic Lupus Erythematosus
Not yet recruiting NCT04234633 - Effect of Gender on Clinical Presentation of SLE ِAt Assiut University Hospitals
Completed NCT01207297 - Tacrolimus Versus Cyclophosphamide as Treatment for Lupus Nephritis Phase 1
Terminated NCT00152555 - Physical Therapy for Systemic Lupus Erythematosus (SLE) N/A
Recruiting NCT05822219 - Vaccine Hesitancy in Black/African Americans With Rheumatic Diseases N/A
Completed NCT04806113 - COVID-19 Vaccine in Immunosuppressed Adults With Autoimmune Diseases Phase 3
Recruiting NCT05966480 - Phase 2 Placebo-Controlled Study to Assess the Safety and Efficacy of ESK-001 in Active Systemic Lupus Erythematosus Phase 2
Completed NCT03155477 - Effect Of Curcuma Xanthorrhiza and Vitamin D3 Supplementation in SLE Patients With Hypovitamin D N/A
Recruiting NCT05342285 - Flow Mediated Dilation in Association With Hyperuricemia
Not yet recruiting NCT03984227 - New Signaling Pathway Targeting Systemic Lupus Erythematosus