The Effect of Liposuction on Menses: a Retrospective Study

Menstrual Irregularity Clinical Trial

Official title:

The Effect of Liposuction on Menses: a Retrospective Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04985591
• Other study ID #: SH9H-2019-T221-2
• Status: Completed
• Phase: Early Phase 1
• Start date: June 14, 2016
• Est. completion date: March 12, 2021

Study information

• Verified date: July 2021
• Source: Shanghai Jiao Tong University School of Medicine
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The prevalence of obesity nearly tripled from 1975 to 2021, resulting in liposuction, as an effective shaping method, to be performed more frequently. Liposuction is a surgical procedure that uses a specialized instrument to suck fat fragments in the subcutaneous fat layer through a small incision. Analyzing a large sample sizes of patients who had liposuction, we found that some female patients underwent menstrual irregularity after liposuction. In 2004, Carolyn et al. reported several cases in which there was a connection between liposuction and an early onset of menses. Further studies showed that an early onset of menses may be related to the volume of adipose tissue extracted, the amount of anesthesia given, the area of liposuction, and body weight. However, the sample of that study was small, as there were only 17 cases included in the statistical model, and there are few articles in which the impact of liposuction on menses has been studied. To better understand whether menstrual irregularity will occur after liposuction, patients with postmenopausal or preoperative menstrual irregularity were excluded, leaving a sample of 518 female patients to be reviewed. A better understanding of the impact of liposuction on menses may help clinical doctors predict the underlying risk of menstrual irregularity after liposuction and identify individuals at higher risk. The findings may contribute to further understanding of menstrual irregularity.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 516
• Est. completion date: March 12, 2021
• Est. primary completion date: March 12, 2021
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 18 Years to 55 Years

Eligibility

Inclusion Criteria:patients who were in 18-55 and have a regular menses - Exclusion Criteria:Patients who were younger than 18 years old or older than 55 years old, who were in the perimenopausal or postmenopausal stage or who had menstrual irregularity before plastic surgery were excluded from both groups. -

Related Conditions & MeSH terms

• Menstrual Irregularity
• Menstruation Disturbances

Intervention

Procedure:
• Liposuction
A small, inconspicuous incision was made in the liposuction group to dislodge fat out of the body.
• Other plastic surgery
Other plastic surgery like blepharoplasty or keloid excision.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Shanghai Jiao Tong University School of Medicine

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	menstrual irregularity	to detect any change in the menses during the following 3 months, post surgery	three months