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Menstrual Cycle Disorder clinical trials

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

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NCT ID: NCT05985980 Recruiting - Clinical trials for Menstrual Cycle Disorder

The Effect of Menstrual Cycle on the Results of Treadmill Exercise Test With High Sensitive Cardiac Troponin Levels After Exercise in Women

Start date: March 1, 2023
Phase:
Study type: Observational

False positive results are commonly observed in women after exercise treadmill test (ETT). The effects of menstrual periodic changes on the results of exercise treadmill test in premenopausal women have not been clearly defined. Primary purpose of the study is to investigate the biological causes of false positive test results in the treadmill exercise test in premenopausal women. Estrogen is known to have direct vasodilatory effects on coronary arteries. Early and late follicular phases of the menstrual cycle are characterized by low and high estrogen levels, respectively. The Early Follicular Phase starts on the first day of the menstrual cycle and ends when oestradiol begins to increase. It is characterised by increasing LH and FSH and constant low levels of oestradiol. The late follicular phase starts with the increase in oestradiol and ends at its preovulatory peak. The hypothesis of the study is that ETT results will change at the early and late follicular phases in premenstrual women. Premenopausal women between the ages of 18-40, who apply to the cardiology outpatient clinics of Göztepe City Hospital with typical/atypical chest pain, and an indication for ETT will be included in the study. ETT will be performed in the early and late follicular phases of the menstrual cycle, separately.