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Hormone Estradiol Replacement Therapy Additional Herbals — WH  

Menopause Clinical Trial

Official title:
The Natural Ingredients and Artificial Made Ready, a Good Combination Reduced the Risk of Thrombosis, Concerns With Their Use of HRT

Clinical Trial Summary

The purpose of this study is to determine whether Hormone Replacement Therapy (HRT), safety studies are combined with herbal (garlic oil, rutin, and nattokinase) to reduce estrogen side effects. Making it safer when an endocrine supplement is needed for estrogen deficiency symptoms in menopausal and postmenopausal women.

Clinical Trial Description

Recent studies have proved : -Garlic oil as garlic may reduce platelet aggregation, patients taking anticoagulant medication are cautioned about consuming garlic. A 2013 meta-analysis concluded that garlic preparations may effectively lower total cholesterol by 11-23 mg/dL and LDL cholesterol by 3-15 mg/dL in adults with high cholesterol if taken for longer than two months. The same analysis found that garlic had a marginally positive effect on HDL cholesterol, no significant effect on blood triglyceride levels, and that garlic preparations were generally well tolerated with very few side effects. - Nattokinase Nattō is made from fermented soybeans and has been eaten in Japan for about a thousand years. Nattō is produced by fermentation by adding the bacterium Bacillus natto to boiled soybeans. Nattokinase is produced by the bacterium acting on the soybeans . While other soy foods contain enzymes, it is only the nattō preparation that contains the specific nattokinase enzyme. - Estradiol valerate is one of the most widely used esters of estradiol. - Progesterone: Hormone replacement therapy. Progesterone is combined with 17-beta estradiol in the estrogen patch. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02618148
Study type Interventional
Source Trieu, Nguyen Thi, M.D.
Contact
Status Completed
Phase Phase 4
Start date January 2009
Completion date June 2015
View Details
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