Menopause Clinical Trial
Official title:
Healthy Transitions: Menopause Effect on Obesity, Energy Balance, and Insulin
The purpose of this study is to determine the effect of menopause on obesity, energy balance, and insulin in postmenopausal, obese women.
The effect of menopause on body composition and cardiovascular risk in healthy caucasian
women has been the subject of much study. In contrast, there are few data available on
menopause in African-American women. Since menopause is associated with potentially
preventable health risks in women, this proposal is aimed at characterizing the
perimenopausal period in terms of body fat, energy balance, and insulin action in both
caucasian and African-American women.
The study will address 4 general hypotheses:
- Menopause increases both total and visceral abdominal fat
- Changes in body composition and body weight at menopause are mediated, at least in part
by changes in 24-hour energy expenditure and/or food intake
- Menopause results in decreased insulin sensitivity that may predispose certain women to
develop diabetes later in life
- African-American women may respond to the shifts in reproductive hormones at menopause
differently than caucasian women.
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Observational Model: Cohort, Time Perspective: Prospective
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT04553029 -
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||
| Completed |
NCT03672513 -
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|
N/A | |
| Terminated |
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|
||
| Completed |
NCT05387174 -
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N/A | |
| Completed |
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RF and PEMF for Treatment of Vaginal Laxity and Mons Pubis and Labia for Improvement of Skin Laxity
|
N/A | |
| Completed |
NCT06057896 -
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|
||
| Completed |
NCT05617287 -
An Exploratory Investigation of Dietary Supplementation and the Effect on Common Symptoms of Perimenopause and Menopause
|
N/A | |
| Recruiting |
NCT05180266 -
Therapeutic Touch and Music in The Menopausal Period
|
N/A | |
| Recruiting |
NCT04043520 -
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|
Phase 4 | |
| Completed |
NCT03663075 -
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|
N/A | |
| Completed |
NCT03363997 -
Pharmacokinetics and Pharmacodynamics of 3 Dosages of Estriol After Continuous Vaginal Administration for 21 Days
|
Phase 1 | |
| Not yet recruiting |
NCT04728126 -
Menopausal Symptoms and Burnout: Comparison of Occupational Health Issue Among Health Professionals in UMC Hospitals
|
||
| Not yet recruiting |
NCT04724135 -
Assessment of Menopause Related Quality of Life Among Health Professionals in University Hospitals of UMC in Nur-Sultan
|
||
| Completed |
NCT02274571 -
Raising Insulin Sensitivity in Post Menopause
|
Early Phase 1 | |
| Completed |
NCT02430987 -
Low Sexual Desire and Metabolic Syndrome
|
N/A | |
| Completed |
NCT02253173 -
Estradiol Vaginal Softgel Capsules in Treating Symptoms of Vulvar and Vaginal Atrophy in Postmenopausal Women
|
Phase 3 | |
| Completed |
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Calorie Restriction With Leucine Supplementation
|
N/A | |
| Recruiting |
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N/A | |
| Terminated |
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|
N/A | |
| Completed |
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|
N/A |