Citation(s)
- Aldrian S, Zak L, Wondrasch B, Albrecht C, Stelzeneder B, Binder H, Kovar F, Trattnig S, Marlovits S
Clinical and radiological long-term outcomes after matrix-induced autologous chondrocyte transplantation: a prospective follow-up at a minimum of 10 years. Am J Sports Med. 2014 Nov;42(11):2680-8. doi: 10.1177/0363546514548160. Epub 2014 Sep 9.
- Anderson DE, Williams RJ 3rd, DeBerardino TM, Taylor DC, Ma CB, Kane MS, Crawford DC
Magnetic Resonance Imaging Characterization and Clinical Outcomes After NeoCart Surgical Therapy as a Primary Reparative Treatment for Knee Cartilage Injuries. Am J Sports Med. 2017 Mar;45(4):875-883. doi: 10.1177/0363546516677255. Epub 2017 Jan 9.
- Beck SE, Jung BH, Fiorino A, Gomez J, Rosario ED, Cabrera BL, Huang SC, Chow JY, Carethers JM
Bone morphogenetic protein signaling and growth suppression in colon cancer. Am J Physiol Gastrointest Liver Physiol. 2006 Jul;291(1):G135-45. doi: 10.1152/ajpgi.00482.2005.
- Cox JS, Nye CE, Schaefer WW, Woodstein IJ
The degenerative effects of partial and total resection of the medial meniscus in dogs' knees. Clin Orthop Relat Res. 1975;(109):178-83. doi: 10.1097/00003086-197506000-00026.
- Crues JV 3rd, Ryu R, Morgan FW
Meniscal pathology. The expanding role of magnetic resonance imaging. Clin Orthop Relat Res. 1990 Mar;(252):80-7.
- Donahue RP, Gonzalez-Leon EA, Hu JC, Athanasiou K
Considerations for translation of tissue engineered fibrocartilage from bench to bedside. J Biomech Eng. 2018 Dec 5;141(7):0708021-07080216. doi: 10.1115/1.4042201. Online ahead of print.
- Farr J, Gracitelli GC, Shah N, Chang EY, Gomoll AH
High Failure Rate of a Decellularized Osteochondral Allograft for the Treatment of Cartilage Lesions. Am J Sports Med. 2016 Aug;44(8):2015-22. doi: 10.1177/0363546516645086. Epub 2016 May 13.
- Filardo G, Kon E, Di Martino A, Busacca M, Altadonna G, Marcacci M
Treatment of knee osteochondritis dissecans with a cell-free biomimetic osteochondral scaffold: clinical and imaging evaluation at 2-year follow-up. Am J Sports Med. 2013 Aug;41(8):1786-93. doi: 10.1177/0363546513490658. Epub 2013 Jun 12.
- Fox AJ, Wanivenhaus F, Burge AJ, Warren RF, Rodeo SA
The human meniscus: a review of anatomy, function, injury, and advances in treatment. Clin Anat. 2015 Mar;28(2):269-87. doi: 10.1002/ca.22456. Epub 2014 Aug 14.
- Fukui T, Ii M, Shoji T, Matsumoto T, Mifune Y, Kawakami Y, Akimaru H, Kawamoto A, Kuroda T, Saito T, Tabata Y, Kuroda R, Kurosaka M, Asahara T
Therapeutic effect of local administration of low-dose simvastatin-conjugated gelatin hydrogel for fracture healing. J Bone Miner Res. 2012 May;27(5):1118-31. doi: 10.1002/jbmr.1558.
- Gupta S, Del Fabbro M, Chang J
The impact of simvastatin intervention on the healing of bone, soft tissue, and TMJ cartilage in dentistry: a systematic review and meta-analysis. Int J Implant Dent. 2019 Apr 9;5(1):17. doi: 10.1186/s40729-019-0168-4.
- Hutchinson ID, Moran CJ, Potter HG, Warren RF, Rodeo SA
Restoration of the meniscus: form and function. Am J Sports Med. 2014 Apr;42(4):987-98. doi: 10.1177/0363546513498503. Epub 2013 Aug 12.
- Kadam UT, Blagojevic M, Belcher J
Statin use and clinical osteoarthritis in the general population: a longitudinal study. J Gen Intern Med. 2013 Jul;28(7):943-9. doi: 10.1007/s11606-013-2382-8. Epub 2013 Mar 8.
- Kramer J, Bartsch M, Krug D, Klinger M, Nitschke M, Rohwedel J
Simvastatin modulates mouse embryonic stem cell-derived chondrogenesis in vitro. Toxicol In Vitro. 2012 Oct;26(7):1170-6. doi: 10.1016/j.tiv.2012.06.013. Epub 2012 Jul 3.
- Lopez-Alvarez M, Lopez-Puente V, Rodriguez-Valencia C, Angelome PC, Liz-Marzan LM, Serra J, Pastoriza-Santos I, Gonzalez P
Osteogenic effects of simvastatin-loaded mesoporous titania thin films. Biomed Mater. 2018 Feb 2;13(2):025017. doi: 10.1088/1748-605X/aa95f1.
- Marlovits S, Singer P, Zeller P, Mandl I, Haller J, Trattnig S
Magnetic resonance observation of cartilage repair tissue (MOCART) for the evaluation of autologous chondrocyte transplantation: determination of interobserver variability and correlation to clinical outcome after 2 years. Eur J Radiol. 2006 Jan;57(1):16-23. doi: 10.1016/j.ejrad.2005.08.007. Epub 2005 Oct 3.
- Marlovits S, Striessnig G, Resinger CT, Aldrian SM, Vecsei V, Imhof H, Trattnig S
Definition of pertinent parameters for the evaluation of articular cartilage repair tissue with high-resolution magnetic resonance imaging. Eur J Radiol. 2004 Dec;52(3):310-9. doi: 10.1016/j.ejrad.2004.03.014.
- Miao Y, Yu JK, Ao YF, Zheng ZZ, Gong X, Leung KK
Diagnostic values of 3 methods for evaluating meniscal healing status after meniscal repair: comparison among second-look arthroscopy, clinical assessment, and magnetic resonance imaging. Am J Sports Med. 2011 Apr;39(4):735-42. doi: 10.1177/0363546510388930. Epub 2011 Jan 10.
- Nepple JJ, Dunn WR, Wright RW
Meniscal repair outcomes at greater than five years: a systematic literature review and meta-analysis. J Bone Joint Surg Am. 2012 Dec 19;94(24):2222-7. doi: 10.2106/JBJS.K.01584.
- Niemeyer P, Laute V, John T, Becher C, Diehl P, Kolombe T, Fay J, Siebold R, Niks M, Fickert S, Zinser W
The Effect of Cell Dose on the Early Magnetic Resonance Morphological Outcomes of Autologous Cell Implantation for Articular Cartilage Defects in the Knee: A Randomized Clinical Trial. Am J Sports Med. 2016 Aug;44(8):2005-14. doi: 10.1177/0363546516646092. Epub 2016 May 20.
- Noyes FR, Barber-Westin SD
Long-term Survivorship and Function of Meniscus Transplantation. Am J Sports Med. 2016 Sep;44(9):2330-8. doi: 10.1177/0363546516646375. Epub 2016 May 20.
- Oka S, Matsumoto T, Kubo S, Matsushita T, Sasaki H, Nishizawa Y, Matsuzaki T, Saito T, Nishida K, Tabata Y, Kurosaka M, Kuroda R
Local administration of low-dose simvastatin-conjugated gelatin hydrogel for tendon-bone healing in anterior cruciate ligament reconstruction. Tissue Eng Part A. 2013 May;19(9-10):1233-43. doi: 10.1089/ten.TEA.2012.0325. Epub 2013 Jan 14.
- Proulx ST, Kwok E, You Z, Papuga MO, Beck CA, Shealy DJ, Ritchlin CT, Awad HA, Boyce BF, Xing L, Schwarz EM
Longitudinal assessment of synovial, lymph node, and bone volumes in inflammatory arthritis in mice by in vivo magnetic resonance imaging and microfocal computed tomography. Arthritis Rheum. 2007 Dec;56(12):4024-37. doi: 10.1002/art.23128.
- Roy TC
Diagnoses and mechanisms of musculoskeletal injuries in an infantry brigade combat team deployed to Afghanistan evaluated by the brigade physical therapist. Mil Med. 2011 Aug;176(8):903-8. doi: 10.7205/milmed-d-11-00006.
- Sanders JW, Putnam SD, Frankart C, Frenck RW, Monteville MR, Riddle MS, Rockabrand DM, Sharp TW, Tribble DR
Impact of illness and non-combat injury during Operations Iraqi Freedom and Enduring Freedom (Afghanistan). Am J Trop Med Hyg. 2005 Oct;73(4):713-9.
- Schreiner MM, Raudner M, Marlovits S, Bohndorf K, Weber M, Zalaudek M, Rohrich S, Szomolanyi P, Filardo G, Windhager R, Trattnig S
The MOCART (Magnetic Resonance Observation of Cartilage Repair Tissue) 2.0 Knee Score and Atlas. Cartilage. 2021 Dec;13(1_suppl):571S-587S. doi: 10.1177/1947603519865308. Epub 2019 Aug 17.
- Skottheim IB, Gedde-Dahl A, Hejazifar S, Hoel K, Asberg A
Statin induced myotoxicity: the lactone forms are more potent than the acid forms in human skeletal muscle cells in vitro. Eur J Pharm Sci. 2008 Apr 23;33(4-5):317-25. doi: 10.1016/j.ejps.2007.12.009. Epub 2008 Jan 18.
- Trattnig S, Ba-Ssalamah A, Pinker K, Plank C, Vecsei V, Marlovits S
Matrix-based autologous chondrocyte implantation for cartilage repair: noninvasive monitoring by high-resolution magnetic resonance imaging. Magn Reson Imaging. 2005 Sep;23(7):779-87. doi: 10.1016/j.mri.2005.04.010. Epub 2005 Aug 26.
- Verdonk P, Dhollander A, Almqvist KF, Verdonk R, Victor J
Treatment of osteochondral lesions in the knee using a cell-free scaffold. Bone Joint J. 2015 Mar;97-B(3):318-23. doi: 10.1302/0301-620X.97B3.34555.
- Vos LM, Kuijer R, Huddleston Slater JJ, Bulstra SK, Stegenga B
Inflammation is more distinct in temporomandibular joint osteoarthritis compared to the knee joint. J Oral Maxillofac Surg. 2014 Jan;72(1):35-40. doi: 10.1016/j.joms.2013.08.022. Epub 2013 Nov 6.
- Wyatt RW, Inacio MC, Liddle KD, Maletis GB
Factors associated with meniscus repair in patients undergoing anterior cruciate ligament reconstruction. Am J Sports Med. 2013 Dec;41(12):2766-71. doi: 10.1177/0363546513503287. Epub 2013 Sep 12.
- Xu H, Bouta EM, Wood RW, Schwarz EM, Wang Y, Xing L
Utilization of longitudinal ultrasound to quantify joint soft-tissue changes in a mouse model of posttraumatic osteoarthritis. Bone Res. 2017 Jun 13;5:17012. doi: 10.1038/boneres.2017.12. eCollection 2017.
- Zhang H, Lin CY
Simvastatin stimulates chondrogenic phenotype of intervertebral disc cells partially through BMP-2 pathway. Spine (Phila Pa 1976). 2008 Jul 15;33(16):E525-31. doi: 10.1097/BRS.0b013e31817c561b.
- Zhang S, Matsushita T, Kuroda R, Nishida K, Matsuzaki T, Matsumoto T, Takayama K, Nagai K, Oka S, Tabata Y, Nagamune K, Kurosaka M
Local Administration of Simvastatin Stimulates Healing of an Avascular Meniscus in a Rabbit Model of a Meniscal Defect. Am J Sports Med. 2016 Jul;44(7):1735-43. doi: 10.1177/0363546516638342. Epub 2016 Apr 11.
- Zhao BJ, Liu YH
Simvastatin induces the osteogenic differentiation of human periodontal ligament stem cells. Fundam Clin Pharmacol. 2014 Oct;28(5):583-92. doi: 10.1111/fcp.12050. Epub 2013 Nov 8.
A Prospective, Randomized, Controlled, Double-Blinded, Multi-Center, Phase 1/2b Study to Evaluate the Safety and Efficacy of AM3101 to Augment Meniscal Healing
Details for clinical trial NCT05560477