Meningitis Clinical Trial
Official title:
Antibody Persistence and Booster Dose Response in Subjects Who Received Menactra® (Meningococcal [Groups A, C, Y, and W-135] Polysaccharide Diphtheria Toxoid Conjugate Vaccine) Three Years Earlier in Study MTA26
Study will evaluate the persistence of antibodies approximately three years after an initial
dose of Menactra® vaccine in toddlers who participated in study MTA26 (NCT00643916) and
age-matched Menactra naive participants.
Objectives:
- To assess the persistence of antibody responses three years after one or two doses of
Menactra® vaccine in subjects who participated in study MTA26.
- To describe the antibody responses to a single dose of Menactra® vaccine in subjects
who had previously received one or two doses of Menactra® vaccine and in Menactra®
vaccine-naïve subjects.
- To describe the safety profile of a single dose of Menactra® vaccine in subjects.
Subjects that received Menactra® vaccine in study MTA26 (NCT00643916) and age-matched Menactra naive participants will receive a single dose of Menactra® on Day 0. They will be evaluated for immunogenicity and safety post-vaccination. ;
Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention
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