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Clinical Trial Summary

In this study, meningioma organoids will be established from patients' tissues and the characterization of the organoid will be performed.


Clinical Trial Description

Aims and Hypothesis to be tested: The investigators hypothesized that the derived organoid should have a similar morphological and genetic mutation signatures to the patient primary tissue. Study period: 1 year for patient recruitment and organoid generation from patient tumor Study population: 30 Study samples: Patient's meningioma tumor sample are collected from patients with surgical needs. Sample collected are used for organoid culture. Morphological and genetic characteristics will be compared between the patient tumor sample and the corresponding derived organoids Primary outcome measures: Whole exome sequencing data of patient tumor tissue and patients-derived organoids ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04478877
Study type Observational
Source Chinese University of Hong Kong
Contact
Status Completed
Phase
Start date May 23, 2020
Completion date August 31, 2023

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