Men Clinical Trial
Official title:
Comparison of the Bioavailability the of a Single Administration of Two Canola Proteins (Hydrolyzate, Isolate) and Soy Protein in Healthy Men.
The objective of the study is to evaluate the nutritional and physiological properties of two canola proteins focusing on the bioavailability in humans.
The physiological effects of a single administration of two different industrially
manufactured canola proteins (hydrolyzate, isolate) were investigated compared to soy
protein.
Twenty-eight healthy men (ø 25 years) completed a double-blind, placebo-controlled,
crossover study. The subjects were randomly divided into two groups (group A: canola protein
isolate and soy protein isolate and group B: canola protein hydrolyzate and soy protein
isolate). After a three-day run-in period, on the intervention day, the subjects consumed a
protein drink containing 30.0 g protein powder added to a final volume of 500 mL tomato
juice. Half of the subjects in each group consumed a protein drink containing 30.0 g canola
protein, the other half received the soy protein. After taking of fasting blood samples in
the morning of the intervention day, blood samples were drawn at regular intervals for a
period of eight hours. At the end of the run-in period and on the intervention day, a
24-hour urine collection took place.
Within a second experiment (after 4 weeks), the protein source was crossed within the four
subgroups for the second intervention.
;
Allocation: Randomized, Endpoint Classification: Bio-availability Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Screening
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