tACS Improves Memory in Elders With Subjective Memory Complaints

Status Completed

Clinical Trial Summary

Subjective memory complaints (SMC), the main cognitive component of which is event memory, is a predictor of Alzheimer's disease in elderly people. The purpose of this study was to investigate the effect of transcranial alternating current stimulation (tACS) with theta frequency (6 Hz) on the medial prefrontal cortex in the improvement of episodic memory in individuals with SMC in a double blind, randomized, and sham-controlled parallel study. Sixteen participants with SMC received either active or sham theta tACS on the medial prefrontal cortex (mPFC). EEG was recorded and Rey Auditory Verbal Learning Test (RAVLT) was administered. The aim of the current study was to see if theta tACS over the mPFC can improve event memory in individuals with SMC and thus can be considered a potential therapeutic intervention for this population or not.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05569902
Study type	Interventional
Source	University of Tehran
Contact
Status	Completed
Phase	N/A
Start date	October 1, 2021
Completion date	August 1, 2022

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT01876758` - Cognitive Training for Memory Deficits Associated With Electroconvulsive Therapy	N/A
Active, not recruiting	`NCT02255799` - Multicenter Evaluation of Memory Remediation After TBI With Donepezil	Phase 3
Completed	`NCT03727737` - Efficacy of Repetitive Transcranial Magnetic Stimulation for Improvement of Memory in Older Adults With TBI	N/A
Recruiting	`NCT06208943` - Neural and Cognitive Consequences of COVID-19 Survival
Completed	`NCT03812744` - Neurophysiological Effects of Whole Coffee Cherry Extract in Older Adults	N/A
Completed	`NCT02790151` - Memory Rehabilitation by Means of Working Memory Training in Combination With a Recollection Training	N/A
Active, not recruiting	`NCT00457769` - Aricept to Improve Functional Tasks in Vascular Dementia	Phase 1
Completed	`NCT03872310` - Cognitive Enhancement on Working Memory in Patients With Schizophrenia	N/A
Terminated	`NCT00531505` - Obesity and Memory, mRNA, Body Composition, Comorbidity Scale	N/A
Terminated	`NCT02864940` - Memory Training in Aneurysmal Subarachnoid Hemorrhage Patients	N/A
Active, not recruiting	`NCT01123018` - Screening for Memory Studies
Completed	`NCT05520424` - An Exploratory Investigation of a Supplement to Promote Brain Health	N/A
Completed	`NCT05523115` - An Exploratory Investigation of a Supplement to Promote Cognitive Health Benefits	N/A
Completed	`NCT05051501` - The Effects of Microbiological Spectrum Changes to Improve Cognitive Health in Aging Population	Phase 2
Completed	`NCT05170464` - The Acute Effects of Exercise and Caffeine on Working Memory During Acute Caffeine Deprivation	Phase 2/Phase 3
Completed	`NCT02680210` - Self-defining Memories in Patients With a TBI	N/A
Completed	`NCT02122224` - Breakfast Consumption in Preschoolers: Satiety, Diet Quality and Memory	N/A
Recruiting	`NCT05363228` - The Effect of Tai Chi and Therapy by Dance and Movement on Blood Irisin Levels in Older Adults Over 65 Years of Age.	N/A
Completed	`NCT01806701` - Brain Response to Treatment for Pediatric PTSD	N/A