Melasma Clinical Trial
Official title:
Comparing Tranexamic Acid Microinjection Alone Versus Its Combination With Fractional Carbon Dioxide Laser in Melasma Treatment
The objective of this study is to assess and compare the efficacy of tranexamic acid
intradermal microinjection alone versus its combination with low power fractional CO2 laser
in a sequential pattern.
In all participants one half of the face will be randomly assigned to low power fractional
CO2 laser while other side to Tranexamic acid intradermal microinjections on the 1st session.
This split face session will be repeated every six weeks for 3 sessions.
In addition, Tranexamic acid intradermal microinjections will be applied for full face at the
2nd and 4th week of each split face session.
The response will be evaluated by the Melanin and erythema Indices which will be measured
using reflectance spectrophotometer, Dermoscopy and photography before starting the study,
two and four weeks after the last session. The sessions will take 4 months for each patient
and another one month free of sessions for follow up.
n/a
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