Melasma Clinical Trial
Official title:
Efficacy of Platelet-rich Plasma in Treatment of Melasma
The application of Platelet Rich Plasma (PRP) on three occasions with an interval of 15 days between each one, is related to a decrease in the intensity of the spots and improvement in the quality of the skin of patients with melasma.
832/5000 Objective: To evaluate the effect of PRP for Melasma treatment. Material and
methods: Prospective cohort with therapeutic intervention. Patients, female, with melasma
were included. Changes in the melanin concentration of the face (MASI), degree of
satisfaction (MELASQOL) and histological changes were clinically evaluated.
The Sp-MELASQOL questionnaire, Fitzpatrick and MASI scales were applied, and photographs were
taken with ambient light and with Wood's light with the Janus-II General Model. The patients
were evaluated and classified, before and after the treatment by means of dermatoscopy, which
was performed using a dermatoscope with polarized light (DermLite DL3N®), which allows an
increase from 6 to 400X.
The dermatoscopy reported the findings of: Quantity, Density and Depth of melasma.
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