Melasma Clinical Trial
Official title:
A Clinical Usage Study to Evaluate the Safety and Efficacy of an Herbal-Based De-Pigmenting System
The purpose of this study is to evaluate the effectiveness and tolerability of an herbal de-pigmenting regimen applied to one side of the face compared with hydroquinone applied to the other side of the face in treating mottled hyperpigmentation and melasma.
This clinical study is being conducted in order to evaluate the effectiveness and
tolerability of a de-pigmenting regimen when used by subjects with mild to severe mottled
hyperpigmentation and melasma. Efficacy will be assessed using visual grading, device
measurements and digital photography. Tolerance and safety will be evaluated by grading for
objective and subjective signs of irritation, and the incidence and severity of adverse
events. Efficacy and tolerance of this product are compared to that of Hydroquinone, which is
applied to one side of the subject's face while the herbal de-pigmenting regimen is applied
to the other side of the face.
The two product pigmentation reducing herbal regimen is based on the novel concept of
inhibiting all 14 major and the 3 branch steps in the melanin cascade.
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