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Clinical Trial Summary

The purpose of this study is to compare the safety and effectiveness of Azelaic Acid Gel to Hydroquinone Cream in the treatment of melasma.


Clinical Trial Description

Melasma is a chronic condition in which dark areas appear on the forehead, cheeks, and upper lips. Hydroquinone is a skin lightener (or fade cream) and is one of the most commonly used medications for the treatment of melasma. Azelaic acid gel is currently used to treat acne and rosacea. ;


Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment


Related Conditions & MeSH terms


NCT number NCT00927771
Study type Interventional
Source Callender Center for Clinical Research
Contact Tracy Brooks
Phone 301.249.0970
Email clinicalresearch@callenderskin.com
Status Recruiting
Phase Phase 4
Start date June 2009
Completion date December 2010

See also
  Status Clinical Trial Phase
Completed NCT01976273 - A Pilot Study Testing 1064nm Q-switch Laser Versus Glycolic Acid Peels for the Treatment of Melasma N/A
Completed NCT05119413 - Comparison of a New Masterful Preparation to Kligman's Trio in the Treatment of Melasma Phase 2
Terminated NCT00863278 - Treatment of Melasma With Stabilized Kligman Preparation Associated or Not With Pulsed Dye Laser Phase 4
Not yet recruiting NCT05930366 - Comparative Evaluation of Microsurgery vs Diode Laser Technique of Gingival Depigmentation N/A
Not yet recruiting NCT05930392 - Comparative Evaluation of Microsurgery vs Conventional Surgical Technique of Gingival Depigmentation N/A
Active, not recruiting NCT01976286 - A Pilot Study Testing Salicylic Acid Peels Versus Glycolic Acid Peels for the Treatment of Melasma N/A
Not yet recruiting NCT03585179 - Oral and Topical Tranexamic Acid for the Treatment of Melasma Phase 3