Identification of Metabolic Phenotypes Associated With Melanoma Metastasis

Status Recruiting

Clinical Trial Summary

The goal of this study is to observe metabolic features associated with human melanoma tumors.

Clinical Trial Description

This is a single center, correlative study designed to assess metabolic features of melanoma tumors in patients. The study will involve the collection of melanoma tissue at the time of surgical biopsy or excision. All samples will be assessed by mass spectrometry for metabolomic analysis. A subset of patients will have received [U-13C]glucose infusions which will be utilized for isotope tracing metabolic analysis. Relevant clinical data (eg survival, metastasis) will be correlated with metabolic findings. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT06400550
Study type	Observational
Source	University of Texas Southwestern Medical Center
Contact	Aleuna Lee
Phone	2146458968
Email	aleuna.lee@utsouthwestern.edu
Status	Recruiting
Phase
Start date	August 1, 2018
Completion date	August 1, 2028

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT04062032` - Metabolomic and Inflammatory Effects of Oral Aspirin (ASA) in Subjects at Risk for Melanoma	Phase 2
Completed	`NCT03620019` - Denosumab + PD-1 in Subjects With Stage III/ IV Melanoma	Phase 2
Active, not recruiting	`NCT03291002` - Study of Intratumoral CV8102 in cMEL, cSCC, hnSCC, and ACC	Phase 1
Completed	`NCT04534309` - Behavioral Weight Loss Program for Cancer Survivors in Maryland	N/A
Completed	`NCT00962845` - Hydroxychloroquine in Patients With Stage III or Stage IV Melanoma That Can Be Removed by Surgery	Early Phase 1
Completed	`NCT00324623` - Cyclophosphamide and Fludarabine Followed by Cellular Adoptive Immunotherapy and Vaccine Therapy in Patients With Metastatic Melanoma	Phase 1
Completed	`NCT00096382` - Cyclophosphamide, Fludarabine, and Total-Body Irradiation Followed By Cellular Adoptive Immunotherapy, Autologous Stem Cell Transplantation, and Interleukin-2 in Treating Patients With Metastatic Melanoma	Phase 2
Completed	`NCT00104845` - Vaccine Therapy in Treating Patients With Stage IIB, Stage IIC, Stage III, or Stage IV Melanoma	Phase 1
Completed	`NCT00072124` - Dacarbazine and/or Cisplatin Compared With Complete Metastasectomy in Treating Patients With Stage IV Melanoma	Phase 3
Completed	`NCT00089193` - Vaccine Therapy With or Without Sargramostim in Treating Patients With Stage IIB, Stage IIC, Stage III, or Stage IV Melanoma	Phase 2
Completed	`NCT00072085` - Immunization With gp100 Protein Vaccine in Treating Patients With Metastatic Melanoma	Phase 2
Active, not recruiting	`NCT00039234` - Interleukin-2 With or Without Histamine Dihydrochloride in Treating Patients With Stage IV Melanoma Metastatic to the Liver	Phase 3
Completed	`NCT00049010` - Diagnostic Study to Predict the Risk of Developing Metastatic Cancer in Patients With Stage I or Stage II Melanoma	N/A
Completed	`NCT00042783` - Vaccine Therapy in Treating Patients With Stage IV Melanoma	Phase 2
Completed	`NCT00006022` - Interleukin-2 Plus Bryostatin 1 in Treating Patients With Melanoma or Kidney Cancer	Phase 1
Completed	`NCT00020358` - Vaccine Therapy in Treating Patients With Melanoma	Phase 2
Completed	`NCT00006385` - Vaccine Therapy With or Without Biological Therapy in Treating Patients With Metastatic Melanoma	Phase 2
Completed	`NCT00005610` - Study of Aerosolized Sargramostim in Treating Patients With Melanoma Metastatic to the Lung	Phase 2
Recruiting	`NCT03767348` - Study of RP1 Monotherapy and RP1 in Combination With Nivolumab	Phase 2
Withdrawn	`NCT00006126` - Peripheral Stem Cell Transplantation in Treating Patients With Melanoma or Small Cell Lung, Breast, Testicular, or Kidney Cancer That is Metastatic or That Cannot Be Treated With Surgery	Phase 1