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Melanoma, Ocular clinical trials

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NCT ID: NCT05402059 Recruiting - Melanoma Clinical Trials

Clinical Outcomes and Biomarkers in Patients With Stage 0-IV Melanoma in Real Clinical Practice

ISABELLA
Start date: March 2, 2022
Phase:
Study type: Observational

Prospective non-interventional study of clinical outcomes and biomarkers in patients with stage 0-IV skin melanoma in real clinical practice

NCT ID: NCT05169957 Active, not recruiting - Metastatic Melanoma Clinical Trials

Hepatic Ablation of Melanoma Metastases to Enhance Immunotherapy Response, a Phase I Clinical Trial (HAMMER I)

Start date: August 9, 2022
Phase: Phase 1
Study type: Interventional

The primary purpose of this study is to determine the feasibility of liver stereotactic body radiation therapy (SBRT) given in combination with systemic therapy (ipilimumab and nivolumab) in adults with metastatic melanoma with liver metastases who are at significant risk of not benefiting from systemic therapy alone.

NCT ID: NCT02678572 Completed - Melanoma, Ocular Clinical Trials

Percutaneous Hepatic Perfusion in Patients With Hepatic-dominant Ocular Melanoma

FOCUS
Start date: February 1, 2016
Phase: Phase 3
Study type: Interventional

This study will evaluate patients who have melanoma that has spread from the eye to the liver: Patients in the study will be treated with Melphalan/HDS up to 6 total treatment, and will be followed until death. This study will evaluate the safety and effects of the treatment on how long patients live and how long it takes for the cancer to advance or respond to the treatment.