Aqueous Deficient Dry Eye Clinical Trial
Official title:
Non-invasive Tear Film Dynamic Measurements in Normal, MGD (Meibomium Gland Dysfunction) and Aqueous Deficient Dry Eye(ADDE) Subjects After Saline Instillation
Compare the objective tear film dynamic measurements in three different populations (MGD
[Meibomium Gland Dysfunction], ADDE [Aqueous Deficient Dry Eye] and normal/control [non-dry
eye]) and the subjective experience before and after instilling a single drop of saline in
each eye.
Currently available office-based tests for dry eye do not reliably correlate with patients'
subjective symptoms. This study is interested in assessing how individuals with these two
different ocular surface diseases compare with the normal population when measured
objectively using two different instruments.
There will be one study day with a single visit that will consist of taking two sets of measurements. Baseline measurements are taken in both eyes using a wavefront sensor to measure visual quality followed by saline instillation. Five minutes after drops, visual quality is again measured to evaluate changes in tear dynamics. ;
Allocation: Non-Randomized, Endpoint Classification: Pharmacodynamics Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Diagnostic