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Medulloblastomas clinical trials

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NCT ID: NCT00749723 Completed - Ependymomas Clinical Trials

Therapy Optimization Trial for the Treatment of Relapsed or Refractory Brain Tumors in Children

HIT-REZ-2005
Start date: February 1, 2006
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to improve overall survival while maintaining a good quality of life in pediatric patients with refractory or recurrent brain tumors (medulloblastomas, supratentorial PNETs, ependymomas WHO grade II and III). Response to different chemotherapy options (intravenous versus oral chemotherapy, intraventricular chemotherapy) as part of a multimodal therapy will be assessed. Progression-free, overall survival and toxicity will be evaluated additionally.

NCT ID: NCT00180947 Recruiting - Clinical trials for Neoplasms, Connective and Soft Tissue

Study of Vinorelbine and Cyclofosfamide Among Patients With Refractory Tumours or in Relapse

Start date: June 2003
Phase: Phase 2
Study type: Interventional

This is a phase II study to determine the antitumor activity of Vinorelbine and Cyclofosfamide association among patients with refractory tumours or in relapse with rhabdomyosarcomas and other soft tissue tumours, Ewing tumours, osteosarcomas, neuroblastomas or medulloblastomas.