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Infusion of Panobinostat (MTX110) Into the Fourth Ventricle or Tumor Resection Cavity in Children and Adults With Recurrent Medulloblastoma

Medulloblastoma Clinical Trial

Official title:
Infusion of Panobinostat (MTX110) Into the Fourth Ventricle or Tumor Resection Cavity in Children and Adults With Recurrent Medulloblastoma: A Pilot Study

Clinical Trial Summary

The purpose of this study is to establish the safety of infusions of panobinostat (MTX110) into the fourth ventricle of the brain or tumor resection cavity in patients with recurrent medulloblastoma and to assess the antitumor activity of simultaneous infusions of panobinostat (MTX110) into the fourth ventricle of the brain or resection cavity in patients with recurrent medulloblastoma based upon MRI scans and lumbar cerebrospinal fluid (CSF) cytology.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04269343
Study type Interventional
Source The University of Texas Health Science Center, Houston
Contact David IIan Sandberg, MD
Phone (713) 500-7370
Email David.I.Sandberg@uth.tmc.edu
Status Not yet recruiting
Phase Early Phase 1
Start date March 2, 2020
Completion date December 30, 2022
View Details
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