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Multicenter Pilot-study for the Therapy of Medulloblastoma of Adults — NOA-07  

Medulloblastoma Clinical Trial

Official title:
Multicenter Pilot-study for the Therapy of Medulloblastoma of Adults (NOA-07)

Clinical Trial Summary

The purpose of this study is to determine whether a combination of a radiochemotherapy (vincristin) and a following maintenance chemotherapy (vincristin, cisplatin and CCNU) in adult patients with medulloblastoma is tolerable.

Clinical Trial Description

As medulloblastoma in adult patients are very rare (1.1% of all brain tumors), adults are often treated in the scope of expanded access treatments or within pediatric studies; although, it is not known whether medulloblastomas act in the same way in adulthood and in childhood. This is the first study to investigate the significance of a combination of a radiochemotherapy (vincristin) and a following maintenance chemotherapy (vincristin, cisplatin and CCNU) in adult patients with medulloblastoma with the purpose to have a starting point for the development of chemotherapeutical protocols in adults. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01614132
Study type Interventional
Source University of Regensburg
Contact
Status Completed
Phase Phase 1/Phase 2
Start date January 2009
Completion date October 2018
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