Chronic Migraine, Headache Clinical Trial
Official title:
Comparison of Effects of Peripheral Nerve Block and Topiramate in the Treatment of Medication Overuse Headaches: A Randomised Parallel Group Study
Purpose: In this study, the investigators compared the effectiveness of peripheral nerve
block (greater occipital nerve block with supratrochlear nerve block) versus topiramate as
detoxification therapies in chronic migraine patients with medication overuse headache.
Methods: At least ninety chronic migraine patients with medication overuse headache are aimed
to include in this study. Patients will be divided into the two groups. The first group will
receive topiramate (n=45, estimated) and the second group will receive nerve block (n=45,
estimated) as detoxification therapy. Patients' records regarding the visual analog scale
(VAS) scores and headache frequencies are aimed to be collected before and after the therapy.
Comparisons regarding VAS scores, headache frequencies, 50% responder rates and 75% responder
rates will be performed in between topiramate and nerve block groups.
n/a
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