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Clinical Trial Summary

Prospective observationnal study, including ICU adult patients with invasive mechanical ventilation for at least 48 hours. Patients are included when performing weaning from mechanical ventilation with pressure support (lowest level of pressure support). Before separating the patient from the ventilator and performing a T tube spontaneous breathing test, diaphragm ultrasound is performed bilaterally : diaphragm excursion, diaphragm thickening fraction and maximal contraction and relaxation velocities with tissue doppler imaging.


Clinical Trial Description

This observationnal study will include patients during weaning from invasive mechanical ventilation: ventilation in pressure support with the lowest level With normal neurological status: glasgow coma scale > 13 Requiring no vasopressor support conventionnal diaphragm parameters: diaphram excursion and thickening fraction will be collected bilaterally with the tissue doppler measures: maximal contraction and relaxation velocities, immediately before a T Tube test. Patients will be divided into 2 groups according to their weaning from mechanicla ventilation outcome, and diaphragm ultrasound patterns will be compared between the 2 groups in order to evaluate the performance of tissue doppler in predicting weaning outcome. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06203353
Study type Observational
Source Mongi Slim Hospital
Contact Mhamed Mebazaa, professor
Phone 22252589
Email msmebazaa@gmail.com
Status Recruiting
Phase
Start date November 1, 2023
Completion date December 30, 2024

See also
  Status Clinical Trial Phase
Completed NCT05539599 - Comprehensive Ultrasound Evaluation as a Predictor of Weaning
Completed NCT01779297 - New Integrated Weaning Indexes N/A
Completed NCT02883465 - Ultrasound Diagnostic for Diaphragmatic Dysfunction in Reanimation N/A