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Clinical Trial Details — Status: Not yet recruiting

Administrative data

NCT number NCT06456788
Other study ID # 344919
Secondary ID
Status Not yet recruiting
Phase
First received
Last updated
Start date July 2024
Est. completion date February 2025

Study information

Verified date May 2024
Source King's College London
Contact Nikki Heinze
Phone 004420 7848 5684
Email nikki.heinze@kcl.ac.uk
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Measles is a highly contagious disease which can result in severe complications in some patients. Healthcare workers have a higher risk of getting measles than the general population because of their increased risk of exposure from patients with measles attending hospitals. Having had measles in the past or at least one dose of the measles, mumps and rubella (MMR) vaccine provides protection (immunity) against measles. UK government guidelines therefore recommend that healthcare workers and non-clinical staff with direct patient contact are fully vaccinated or have other evidence of immunity. Yet, evidence from recent measles outbreaks suggests that some healthcare workers are not immune or do not know if they are immune, with implications for containment efforts, cost and transmission. The purpose of this study is to identify barriers and facilitators to uptake of the MMR vaccine among healthcare workers at King's College Hospital NHS Foundation Trust (KCH). KCH healthcare workers will be eligible to take part in the study if they are aged 18 and over and have direct contact with patients. In addition, the research will focus on four subgroups of healthcare workers at KCH: those who are not immune, those who have not completed the full vaccination schedule, those who don't know their immunity status, those received the vaccine only after joining KCH. The latter may provide insights into facilitators to vaccine uptake. Measles immunity forms part of the occupational health screening at KCH. A series of semi structured interviews lasting approximately 1 hour will explore participants' experiences of the occupational health vaccine screening process and measles vaccine campaigns at KCH; why they are unvaccinated/not fully vaccinated/do not know if they are immune/decided to be vaccinated after joining KCH; and what measures or interventions may help healthcare workers when deciding whether to get the MMR vaccine.


Recruitment information / eligibility

Status Not yet recruiting
Enrollment 30
Est. completion date February 2025
Est. primary completion date October 2024
Accepts healthy volunteers
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - Are aged 18 and over - Currently work as a healthcare worker at KCH - Have direct contact with patients - Don't know if they have had measles and don't know if they have been vaccinated - Or: Have not had measles and have not received the MMR vaccine - Or: Have only received 1 dose of the MMR vaccine - Or: Received the MMR vaccine after joining KCH Exclusion Criteria: - Are aged <18 years old - Work in a role at KCH that does not involve direct contact with patients (e.g., administrative or business staff) - Have had measles in the past or both doses of the MMR vaccine before joining KCH - Are not able to give informed consent

Study Design


Related Conditions & MeSH terms


Intervention

Biological:
MMR vaccination
MMR vaccination status

Locations

Country Name City State
n/a

Sponsors (3)

Lead Sponsor Collaborator
King's College London King's College Hospital NHS Trust, UK Health Security Agency

Outcome

Type Measure Description Time frame Safety issue
Primary Barriers to MMR vaccination Barriers to MMR vaccination will be explored in the qualitative interview Collected at one timepoint 1 day during qualitative interview
Primary Facilitators to MMR vaccination Facilitators to MMR vaccination will be explored in the qualitative interview Collected at one timepoint 1 day during qualitative interview
Primary Reasons for not knowing immunity status Reasons for not knowing immunity status will be explored in the qualitative interview Collected at one timepoint 1 day during qualitative interview
Secondary Experiences of the occupational health vaccine screening process at KCH Experiences of the occupational health vaccine screening process at KCH will be explored in the qualitative interview Collected at one timepoint 1 day during qualitative interview
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