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Measles clinical trials

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NCT ID: NCT00168571 Completed - Measles Clinical Trials

Long-term Follow-up of Measles Antibodies

Start date: March 2002
Phase: Phase 4
Study type: Interventional

Few data exist on long-term persistence of measles antibodies after vaccination of West African infants. The data that do exist indicate that the antibody titres decline very rapidly. Our data would be the first to describe the persistence of measles antibodies after two doses of measles vaccine, and the study would allow us to identify unprotected children and offer them revaccination. Since persistence of measles antibodies is of crucial importance to measles control, the study will contribute significantly to the existing knowledge and might have important implications for future eradication programmes.

NCT ID: NCT00168558 Completed - Measles Clinical Trials

Early Two-dose Measles Vaccination Trial

Start date: July 2003
Phase: Phase 4
Study type: Interventional

The specific aims are to examine in Guinea-Bissau: - whether the standard titre Schwarz (SW) or standard-titre Edmonston-Zagreb (EZ) measles vaccine will be the best vaccine strain for use in a routine one-dose measles vaccination schedule and a two-dose measles vaccination schedule in terms of antibody response, protection against measles and child survival, and - whether the standard-titre Edmonston-Zagreb (EZ) vaccine will be suitable for use in a very early two-dose schedule vaccinating at 4½ and 9 months of age

NCT ID: NCT00168545 Completed - Tetanus Clinical Trials

Immunology of Non-specific Effects of Vaccine

Start date: January 2006
Phase: Phase 4
Study type: Interventional

OBJECTIVES - General: To investigate the immunological background for the non-specific effects of diphtheria-tetanus-pertussis (DTP) and measles vaccines on child mortality - Specific: Examine the cytokine responses and possible association with morbidity in a study of DTP vaccinated children who will be randomised to receive a measles vaccine or no vaccine at 4½ months of age. (All children will receive a measles vaccine at 9 months of age)

NCT ID: NCT00168532 Completed - Measles Clinical Trials

Prophylactic Antibiotics in Measles

Start date: January 1998
Phase: Phase 3
Study type: Interventional

Objective It is the objective to test whether the use of prophylactic antibiotics in measles infection will reduce the incidence of post-measles pneumonia and/or admissions to hospital with 50%. The possible impact on other complications of severe measles will also be measured.

NCT ID: NCT00138255 Terminated - Measles Clinical Trials

Responses of Premature Infants to Measles-Mumps-Rubella (MMR) and Varicella Vaccines

Start date: June 2004
Phase: Phase 4
Study type: Observational

The purpose of this study is to see if the MMR and chickenpox vaccines work as well in premature infants as in children that were carried to full term. A group of children who were carried full-term will be matched for age, sex, and race and will be used for comparison.

NCT ID: NCT00127023 Completed - Measles Clinical Trials

Immunogenicity and Safety of a Combined Vaccine to Prevent Measles, Mumps, Rubella and Chickenpox Diseases

Start date: May 2005
Phase: Phase 3
Study type: Interventional

This is a study to evaluate the immunogenicity and safety of GlaxoSmithKline (GSK) Biologicals combined measles-mumps-rubella varicella candidate vaccine given to healthy children in their second year of life.

NCT ID: NCT00127010 Completed - Measles Clinical Trials

Immunogenicity and Safety of a Combined Vaccine to Prevent Measles, Mumps, Rubella and Chickenpox Diseases

Start date: November 2005
Phase: Phase 3
Study type: Interventional

This is a study to evaluate the immunogenicity and safety of GlaxoSmithKline (GSK) Biologicals combined measles-mumps-rubella varicella candidate vaccine given to healthy children in their second year of life.

NCT ID: NCT00126997 Completed - Measles Clinical Trials

Immunogenicity and Safety of Combined Vaccine to Prevent Measles, Mumps, Rubella and Chickenpox Diseases

Start date: May 2005
Phase: Phase 4
Study type: Interventional

This is a study to assess the immunogenicity and safety of GlaxoSmithKline (GSK) Biologicals live attenuated measles-mumps-rubella-varicella vaccine given to healthy children in their second year of life.

NCT ID: NCT00109343 Completed - Measles Clinical Trials

V221 Concomitant Use Study With Pneumococcal Conjugate Vaccine (V221-019)

Start date: March 2006
Phase: Phase 3
Study type: Interventional

The study is being conducted to demonstrate that V221 may be administered concomitantly with pneumococcal conjugate vaccine without impairing the safety or immunogenicity of measles, mumps, rubella, varicella, or the 7 serotypes of S. pneumoniae.

NCT ID: NCT00109278 Completed - Measles Clinical Trials

A Measles, Mumps, and Rubella Investigational Vaccine Trial (V205C-010)(COMPLETED)

Start date: October 2004
Phase: Phase 2
Study type: Interventional

The purpose of this study is to test the safety of a measles, mumps, and rubella study vaccine made from a new measles stock seed (a component of the vaccine made in 2003) with rHA (recombinant human albumin).