Impact of Nociception Level (NOL)-Guided Remifentanil Infusion on Intraoperative Arterial Pressure and Vasopressor Necessity

Maxillofacial Surgery Clinical Trial

Official title:
Impact of Nociception Level (NOL)-Guided Remifentanil Infusion and Entropy-guided Propofol Infusion on Intraoperative Arterial Pressure and Vasopressor Necessity A Prospective, Randomized, Controlled Trial.

Status Recruiting

Clinical Trial Summary

The aim of this study is to determine if Nociception Level (NOL)-guided Remifentanil analgesia, combined with Entropy-guided Propofol anesthesia, has a significant beneficial effect on the incidence of intraoperative hypotension episodes and/or on vasopressor requirements, during long-lasting major surgeries for high risk patients. The investigator will also investigate the effects of guided anesthesia on postoperative Myocardial Injury in Non-cardiac Surgery (MINS) and Postoperative cognitive dysfunction (POCD), amongst other frequent postoperative complications, in this population.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Maxillofacial Surgery

Clinical Trial Details

NCT number	NCT04963036
Study type	Interventional
Source	Centre Hospitalier Universitaire Saint Pierre
Contact	Panayota Kapessidou, MD,PhD
Phone	+32.2.535
Email	pkapessi@ulb.ac.be
Status	Recruiting
Phase	N/A
Start date	July 28, 2021
Completion date	June 2022

View Details

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