Masticatory System Clinical Trial
Official title:
Impact of Comorbidities Among Adolescents Infected Pain Associated With Disorders of the Masticatory System
The pain associated with disorders of the masticatory system (DAM) include pain in the
masticatory muscles, temporomandibular joints, or deux.1-5 In terms of frequency, the DAM is
the second musculoskeletal disorder most common behind chronic pain in the dos.
Pain associated with DAM not interested adults; they were also observed in adolescents
(2-6%) 7 with significant changes in their quality of life.8 The annual incidence of pain
associated with DAM is 2.6% among adolescents and 3.9% for adults. 9 half to two-thirds of
patients affected by DAM resorted to professional care, and one-third continued to be
subjected to moderate pain and incapacity to severe, regardless of treatment given.
Co-morbidities were identified in adults 12-14, children and adolescents with pain related
to DAM, the United States and Suède. The most common painful co-morbidities among children
and adolescents were headaches, neck, back, limbs or abdomen.
The reasons for the co-existence of DAM with other painful conditions are not well
understood. Nevertheless, it has been demonstrated in adults that they contributed to
apparition and persistence DAM beyond healing time conventionally predicted; they increased
deterioration state health and could complicate significantly the diagnosis and efficacy of
treatment.
Co-morbidity is defined as "the simultaneous existence and the occur two or more diseases,
medically diagnosed in the same person.
The prevalence of several chronic painful conditions appears to be greater among people of
low socioeconomic status compared with those of higher and higher socioeconomic status among
women than hommes.
head pain is commonly reported in the general population (46%) The headache prevalence
ranges from 9% to 97% among adults and 30% to 94% among Adolescents with DAM.
Women have a higher probability have pain related to DAM (odds ratio (OR) = 2.2, 95%
confidence interval (CI): 2.1-2.4) or headache (OR = 2.5, 95% CI: 2.4-2.5) than men.
Cross-sectional studies and case-control demonstrated that subjects with DAM-related pain
were 1.5 to 8.8 times more likely to have headaches compared to those without pain
associated with DAM.
The relationship between headaches and DAM n`est unclear. Both conditions seem to share
similar pathophysiological mechanisms that would promote the development of both diseases in
a individual. Patients affected by headaches are more likely to develop a DAM? A cohort
study showed that adolescents affected by headaches, the chance of developing pain related
to DAM was 2.7 times (95% CI: 1.6-4.4) than adolescents without headaches. Conversely, the
probability of having headache increases with the number of symptoms according to a
relationship of DAM.
Following the results of these studies cited before, it is now necessary to confirm the
relationship between headaches and DAM among adolescents.
Neck pain and back are symptoms commonly reported in adults with DAM (35% to 44%). 23 The
adults affected by DAM have smaller mobility angles in the cervical and more sensitive
points to trapezoids when compared to those without DAM.
Cross-sectional studies and case-control have demonstrated that adult patients with
DAM-related pain had 2.6 to 5 times more likely have back pain than individuals without pain
related to DAM. Chances pain joint (OR = 4.0, 95% CI: 3.7-4.3) are larger among adults
affected by DAM related pain compared to those indemnes. adults affected by DAM-related pain
were also more likely to experience neck pain (OR = 4.0 to 7.9).
Adult women affected by DAM-related pain are more likely to have pain in the neck (OR = 1.5;
95% CI: 1.4-1.8) and back (OR = 1.2; 95% CI: 1.2-1.3) compared to hommes a prospective
cohort study demonstrated that there was a greater likelihood of pain related to DAM among
adolescents affected by back pain compared to those not affected (OR = 3.0, 95% CI: 2.2-6.8)
Our study aims to seek more evidence on the supposed relationship between pain related to
DAM and sore neck or back in the adolescent population.
The irritable bowel syndrome (CIS; 9% to 16%), interstitial cystitis (17%), and stomach pain
(34%) are rated among adults affected by DAM. Adults affected by DAM were 2.7 times (95% CI:
1.4-5.1) more likely to have irritable bowel syndrome than subjects of the same age not
affected. teenagers affected by DAM were 1.5 times (95% CI: 1.0- 2.1) over have luck stomach
upset that the subjects of the same age unaffected.
| Status | Completed |
| Enrollment | 566 |
| Est. completion date | February 2016 |
| Est. primary completion date | February 2016 |
| Accepts healthy volunteers | Accepts Healthy Volunteers |
| Gender | Both |
| Age group | 14 Years to 16 Years |
| Eligibility |
Inclusion Criteria: - adolescents between 14 and 16 - agree to complete an anonymous survey Exclusion Criteria: |
Observational Model: Cohort, Time Perspective: Prospective
| Country | Name | City | State |
|---|---|---|---|
| France | CHU Nice | Nice |
| Lead Sponsor | Collaborator |
|---|---|
| Centre Hospitalier Universitaire de Nice |
France,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | number of painful co-morbidities of DAM among adolescents | identification of co-morbidities by survey analyses | 12 months | No |
| Secondary | number of non-painful co-morbidities of DAM among adolescents | identification of co-morbidities by survey analyses | 12 months | No |