Effects of Massage Versus Rest on Hormones

Massage Clinical Trial

Official title:

Investigating the Effects of Massage vs. Rest on Oxytocin, ACTH, and B-endorphins

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01351402
• Other study ID #: 00012002
• Status: Completed
• Phase: N/A
• First received: May 6, 2011
• Last updated: May 9, 2011
• Start date: June 2006
• Est. completion date: January 2007

Study information

• Verified date: August 2005
• Source: Claremont Graduate University
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Interventional

Clinical Trial Summary

This study will investigate the effects of 15 minutes of massage compared to 15 minutes of quiet rest on physiological variables. Specifically, the investigators will measure the effects on levels of the social hormone oxytocin, and on other physiological variables that interact with oxytocin or that may be influenced by massage (including ACTH, Beta-endorphin, and IL-1alpha). The investigators will also investigate whether, in the case of hormones changes, these influence social decision making.

Description:

Interested participants will have the experiment explained both verbally and in writing, and asked to give their informed consent in writing. After consent, the participants will be led to a private room for their first 30ml blood draw by a qualified phlebotomist. Participants will then have a second 30ml blood draw.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 95
• Est. completion date: January 2007
• Est. primary completion date: August 2006
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Anyone English speaking and over the age of 18.

Exclusion Criteria:

• Minors and anyone who has used illicit drugs or alcohol in the last 24 hours.

Study Design

Allocation: Randomized, Masking: Single Blind, Primary Purpose: Basic Science

Related Conditions & MeSH terms

• Massage
• Rest

Intervention

Procedure:
• Massage or Rest
Participants either received 15 minutes of moderate pressure Swedish massage on the upper back, or rested quietly sitting in a chair for 15 minutes.

Locations

Country	Name	City	State
United States	Cassel, UCLA	Los Angeles	California

Sponsors (2)

Lead Sponsor	Collaborator
Claremont Graduate University	Gruter Institute

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Oxytocin	Participants receive a blood draw at baseline and immediately following 15 minutes of massage or rest and oxytocin will be measured from this sample.	Within 5 minutes following experimental manipulation of either 15 minutes massage or rest.	No
Secondary	Adrenocorticotrophic hormone (ACTH)	Participants will receive a blood draw at baseline and immediately following 15 minutes of massage or rest, and ACTH will be measured in these blood samples.	Within 5 minutes following experimental manipulation of either 15 minutes massage or rest.
Secondary	Beta-endorphin	Participants will receive a blood draw at baseline and immediately following 15 minutes of massage or rest, and B-endorphin will be measured from these samples.	Within 5 minutes following experimental manipulation of either 15 minutes massage or rest.
Secondary	Interleukin-1alpha (IL-1a)	Participants will receive a blood draw at baseline and immediately following 15 minutes of massage or rest, and IL-1a will be measured from these samples.	Within 5 minutes following experimental manipulation of either 15 minutes massage or rest.