Attempts to Stop/Reduce Marijuana Among Dependent Users

Marijuana Abuse Clinical Trial

Official title:

Attempts to Stop/Reduce Marijuana Among Dependent Users

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01039415
• Other study ID #: CHRBS #09-005
• Secondary ID: R01DA024691
• Status: Completed
• Phase: N/A
• First received: December 24, 2009
• Last updated: October 27, 2016
• Start date: June 2010
• Est. completion date: October 2012

Study information

• Verified date: October 2016
• Source: University of Vermont
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Observational

Clinical Trial Summary

The purpose of the study is to determine why and how marijuana users stop or reduce their marijuana use.

Description:

The major aim of this study is to provide a better understanding of attempts to stop or reduce marijuana use that can be used to develop better behavioral treatments for marijuana dependence. The application will focus on adult daily marijuana users who try to stop or reduce their marijuana use in a real-world setting. Although prospective, natural history studies describing attempts to stop or reduce alcohol, heroin and tobacco use have proved useful, we know of no such study among adult marijuana users. Two pilot studies will develop measures and assess compliance with our procedures. The main study will recruit up to 400 adult marijuana smokers with the goal of a sample size of 200 participants with adequate compliance. Participants will call an Interactive Voice Recording (IVR) system daily for 3 months to report marijuana use, quit/reduction attempts, and events that might increase or decrease the probability of initiating a quit/reduction attempt or the success of an attempt. Follow-up at 6 months will track recent marijuana and other drug use. Knowing what motivates marijuana users to try to stop or reduce, and knowing which strategies for stopping marijuana use are successful, can help develop treatments for marijuana dependence. For example, if stopping tobacco when trying to stop marijuana decreases the chance of stopping marijuana, then smoking cessation should be done after stopping marijuana. Or if reducing marijuana often leads to cessation, then convincing those not interested in quitting marijuana to first try reducing may be helpful.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 234
• Est. completion date: October 2012
• Est. primary completion date: October 2012
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• daily marijuana smokers for at least 1 year

Exclusion Criteria:

• pregnant women

Study Design

Observational Model: Case-Only, Time Perspective: Prospective

Related Conditions & MeSH terms

• Marijuana Abuse
• Marijuana Dependence

Locations

Country	Name	City	State
United States	University of Vermont	Burlington	Vermont

Sponsors (2)

Lead Sponsor	Collaborator
University of Vermont	National Institute on Drug Abuse (NIDA)

Country where clinical trial is conducted

United States, 

References & Publications (3)

Hughes JR, Fingar JR, Budney AJ, Naud S, Helzer JE, Callas PW. Marijuana use and intoxication among daily users: an intensive longitudinal study. Addict Behav. 2014 Oct;39(10):1464-70. doi: 10.1016/j.addbeh.2014.05.024. — View Citation

Hughes JR, Naud S, Budney AJ, Fingar JR, Callas PW. Attempts to stop or reduce daily cannabis use: An intensive natural history study. Psychol Addict Behav. 2016 May;30(3):389-97. doi: 10.1037/adb0000155. — View Citation

Hughes JR, Naud S, Budney AJ, Fingar JR, Callas PW. Environmental cues and attempts to change in daily cannabis users: An intensive longitudinal study. Drug Alcohol Depend. 2016 Apr 1;161:15-20. doi: 10.1016/j.drugalcdep.2015.09.033. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	initiation of a quit or reduction attempt		during 3 months of monitoring	No
Secondary	duration of a quit attempt		during the 3 months of monitoring	No