Efficacy of Contingency Management in the Treatment of Adolescents With Cannabis Use Disorders

Marijuana Abuse Clinical Trial

Official title:

Efficacy of a Contingency Management Program in the Treatment of Adolescents With Cannabis Use Disorders in a Child and Adolescent Psychiatry and Psychology Department

Clinical Trial Details — Status: Unknown status

Administrative data

• NCT number: NCT00878852
• Other study ID #: PI08/90331
• Secondary ID: 4363/2008 (Ethic
• Status: Unknown status
• Phase: N/A
• First received: April 8, 2009
• Last updated: May 20, 2009
• Start date: April 2009

Study information

• Verified date: May 2009
• Source: Hospital Clinic of Barcelona
• Contact: Javier Goti, M.D
• Phone: 0034932279970
• Email: jgoti[@]clinic.ub.es
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Cannabis use among Spanish adolescents has been increasing in the last decade. It has been related to poor school achievement, delinquency, substance use and psychiatric disorders. Furthermore, psychoactive substance use in adolescents presenting psychiatric disorders can result in the development of substance use disorders or the worsening of psychopathology. Thus, there's an urge to develop efficient interventions in the treatment of these disorders. Therapeutic approaches based on cognitive-behavioural therapy and motivational interviewing have demonstrated a limited efficacy in this population. Programs based on contingency management have been reported to be useful both in adult and adolescents, too. But it still remains unclear whether a combination of these therapeutic approaches is feasible and brings a better cost-benefit relation.

The investigators' project aims to evaluate the added benefits of supplementing a standard intervention on cannabis use, based on combined approach that includes motivational and cognitive-behavioural elements, with a contingency management program. Therefore, pre and post-treatment evaluation will be carried forward in a sample of 30 adolescents (aged 12-18) that initiate treatment for cannabis use related disorder at the Child and Adolescent Psychiatry Department of the Hospital Clinic in Barcelona. Participants will be randomly assigned to a standard treatment group or an experimental group in which standard treatment will be supplemented with a contingency management protocol. As a secondary objective, a prospective assessment of neuropsychological performance related to cannabis use or abstinence will be carried forward.

Recruitment information / eligibility

• Status: Unknown status
• Enrollment: 30
• Est. primary completion date: December 2010
• Accepts healthy volunteers: No
• Gender: All
• Age group: 12 Years to 18 Years

Eligibility

Inclusion Criteria:

• Presence of DSM-IV-TR criteria of cannabis abuse and/or dependence

• Signed informed consent

Exclusion Criteria:

• Mental retardation

• Presence of a substance use disorder other than nicotine or cannabis

• Severe or unstable medical

• Presence at the moment of inclusion of severe acute psychopathology (acute psychotic symptoms, severe depressive symptoms, suicidal ideation)

Related Conditions & MeSH terms

• Marijuana Abuse

Intervention

Behavioral:
• Standard treatment
Participants will be randomly assigned to a standard treatment group. Patients allocated to this group will receive active treatment in form of 12-session intervention program. This program includes weekly intervention sessions developed according to the MET/CBT12 treatment protocol (Sampl, Kadden, 2001). Intervention includes Motivational interviewing (2 sessions) and Cognitive behavioral therapy
• Standard Treatment Plus Contingency Management Program
Participants assigned to this group will receive active treatment in form of 12-session intervention program. This program includes weekly intervention sessions developed according to the MET/CBT12 treatment protocol (Sampl, Kadden, 2001). Intervention includes Motivational interviewing (2 sessions) and Cognitive behavioral therapy (10 sessions). This treatment protocol will be supplemented with a contingency management intervention. Intervention will consist in a voucher program: negative urine-screens will be rewarded with vouchers. Voucher will have an increasing value. At the end of the program, vouchers can be changed by gifts. Potential gifts will be selected by the therapists and will be related to pro-social activities, aiming to change preexisting risk behaviours.

Locations

Country	Name	City	State
Spain	Hospital Clinic Barcelona	Barcelona

Sponsors (1)

Lead Sponsor	Collaborator
Hospital Clinic of Barcelona

Country where clinical trial is conducted

Spain, 

References & Publications (1)

Stephens RS, Babor TF, Kadden R, Miller M; Marijuana Treatment Project Research Group. The Marijuana Treatment Project: rationale, design and participant characteristics. Addiction. 2002 Dec;97 Suppl 1:109-24. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Percentage of marijuana active users		12 weeks
Secondary	Percentage of negative urine-screens		12 weeks
Secondary	Percentage of completed intervention sessions		12 weeks
Secondary	Scores in psychopathology and drug scales (T-ASI, SDQ, BDI, Cannabis Problem Questionnaire)		12 weeks