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Marijuana Abuse clinical trials

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NCT ID: NCT00249509 Completed - Marijuana Abuse Clinical Trials

Effectiveness of Nefazodone and Bupropion in Treating Marijuana Dependent Individuals

Start date: September 2000
Phase: Phase 2
Study type: Interventional

Recent research has identified the following withdrawal symptoms to be associated with abruptly stopping marijuana use: anxiety, irritability, bodily aches and pains, and difficulty sleeping. These symptoms resemble those of both depression and nicotine withdrawal, suggesting that a similar treatment drug may be useful. This study will evaluate the effectiveness of two antidepressant drugs, bupropion and nefazodone, in reducing withdrawal symptoms in marijuana dependent individuals.

NCT ID: NCT00227916 Completed - Marijuana Abuse Clinical Trials

Motivational Interviews for Incarcerated Teens - 1

Start date: November 2000
Phase: N/A
Study type: Interventional

The purpose of this study is to test the efficacy of an individual motivational interview for reducing alcohol and marijuana-related harm as well as alcohol and marijuana use in incarcerated teens.

NCT ID: NCT00227903 Completed - Alcohol Abuse Clinical Trials

Therapeutic Substance Abuse Treatment in Pregnancy - 1

PRIDE-P
Start date: September 2004
Phase: Phase 2
Study type: Interventional

The purpose of this study is... To assess whether a behavioral treatment that combines motivational enhancement and cognitive skills training therapy (MET-CBT) is more effective than brief advice in: 1) decreasing use of a full range of psychoactive substances (e.g. marijuana, cocaine, methamphetamines, alcohol, nicotine, opioids) in pregnant substance using and dependent women; 2) decreasing HIV risk behavior; 3) improving birth outcomes (longer gestations and greater birth weight).

NCT ID: NCT00227864 Completed - Marijuana Abuse Clinical Trials

A Brief Marijuana Intervention for Adolescent Women - 1

Start date: September 2004
Phase: Phase 3
Study type: Interventional

The purpose of this study is to examine the efficacy of a brief motivational intervention on marijuana use and sex-risk behavior in young women.

NCT ID: NCT00218517 Completed - Marijuana Abuse Clinical Trials

Effectiveness of Selegiline in Treating Marijuana Dependent Individuals - 1

Start date: March 2005
Phase: Phase 2
Study type: Interventional

During the past 15 years, the demand for treatment for marijuana-related problems in the United States has increased nearly twofold. Selegiline is a medication currently used to treat nicotine dependence. The purpose of this study is to evaluate whether selegiline may be useful in treating individuals with marijuana dependence.

NCT ID: NCT00218504 Completed - Marijuana Abuse Clinical Trials

Responses to Marijuana-Related Cues Versus Neutral Cues in Adults Taking Tetrahydrocannabinol (THC) - 2

Start date: December 2005
Phase: Phase 1
Study type: Observational

The majority of past research on marijuana treatment has targeted the alleviation of withdrawal symptoms. Minimal focus has been placed on how altering craving effects may play a role in treating marijuana addiction. Treatment with tetrahydrocannabinol (THC), the main ingredient in marijuana responsible for its reinforcing effects, may decrease marijuana cravings. The purpose of this study is to evaluate the effect of THC pre-treatment on responses to marijuana-related cues versus non marijuana-related cues in individuals addicted to marijuana.

NCT ID: NCT00218478 Completed - Marijuana Abuse Clinical Trials

Evaluating Responses to Drug-Related Cues Versus Neutral Cues to Understand the Effects of Marijuana Craving - 1

Start date: September 2004
Phase: Phase 1
Study type: Observational

The majority of past research on marijuana treatment has specifically targeted the alleviation of withdrawal symptoms. Minimal focus has been placed on how altering craving effects may play a role in treating marijuana addiction. The purpose of this study is to compare the effects of marijuana-related cues versus non marijuana-related cues in individuals both addicted and not addicted to marijuana. In turn, this may help establish a better understanding of the effects of marijuana cravings and may lead to improved treatments for marijuana dependence.

NCT ID: NCT00218114 Completed - Marijuana Abuse Clinical Trials

Divalproex Sodium (Depakote) for Explosive Tempers in Adolescents and Adults

Start date: February 2000
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the effectiveness of divalproex sodium (Depakote) versus placebo in treating disruptive behavior disorder and explosive tempers in adolescents and adults.

NCT ID: NCT00217971 Completed - Marijuana Abuse Clinical Trials

Dronabinol Treatment for Marijuana Addiction

MARINOL
Start date: March 2005
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine if dronabinol decreases the symptoms of marijuana addiction and withdrawal.

NCT ID: NCT00167297 Completed - Cannabis Dependence Clinical Trials

Atomoxetine for the Treatment of Cannabis Dependence

Start date: November 2004
Phase: Phase 2
Study type: Interventional

The purpose of this small open-label trial is to evaluate the feasibility of recruiting cannabis dependent patients for treatment with Atomoxetine and MIT. The clinical data to date on Atomoxetine has been limited to children and adults with attention deficit disorder without co-morbid substance dependence. However, one study estimated that adults with attention deficit disorder have rates of drug abuse three to four times higher than controls (Mannuzza S 1998). The study also reported that cannabis and cocaine are most frequently abused in this population.