BTK Inhibitor DTRMWXHS-12 in Mantle Cell Lymphoma

Status Completed

Clinical Trial Summary

The Primary Objective is to evaluate the safety and tolerability of the DTRMWXHS-12 capsule in patients with relapsed/refractory MCL and recommend the dose and dosing method (RP2D) used in phase II study. The Secondary Objective is to evaluate the pharmacokinetics (PK) of multiple dose oral administration of DTRMWXHS-12 capsule in patients with relapsed/refractory MCL. The Exploratory Objective is to preliminarily evaluate the efficacy of DTRMWXHS-12 capsule in patients with relapsed/refractory MCL.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03836768
Study type	Interventional
Source	Zhejiang DTRM Biopharma
Contact
Status	Completed
Phase	Phase 1
Start date	January 11, 2019
Completion date	November 17, 2021

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