More-2-Eat Phase 2: Scaling and Spread of the Integrated Nutrition Pathway for Acute Care

Malnutrition Clinical Trial

Official title:

More-2-Eat Phase 2: Spread/Scaling up Improved Nutrition Care to Detect and Treat Hospital Malnutrition.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03391752
• Other study ID #: KT2017-01
• Status: Completed
• Start date: May 1, 2018
• Est. completion date: December 31, 2019

Study information

• Verified date: February 2020
• Source: University of Waterloo
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

More-2-Eat Phase 2 provides the opportunity to extend the implementation of the Integrated Nutrition Pathway to a total of 10 hospitals and more than 20 medical/surgical units. Building on the success of More-2-Eat Phase 1, key components of this implementation study will be a registry for self-managed data entry and reports and a community of practice to support implementation of nutrition screening at admission to hospital, subjective global assessment to diagnose and triage patients to care pathways and medication pass of a small amount of nutrient dense oral nutritional supplement. Success with implementation and impact on key patient outcomes will be determined.

Description:

Malnutrition in hospital patients is a growing problem, with 20-45% of patients already malnourished at admission. As 70% of malnourished patients are also frail, early detection and treatment of malnutrition is one way to improve the outcomes of frail older adults. To improve the detection and treatment of these conditions, the PI developed the Integrated Nutrition Pathway for Acute Care (INPAC) that guides hospital staff on when to conduct key nutrition care activities to improve outcomes (e.g. screening at admission).

In More-2-Eat (April 2015-March 2017), 5 Canadian hospital units in 4 provinces received funding to implement INPAC. Each hospital, with support from a research team had 1 year to implement INPAC. All 5 hospitals were successful in improving detection and treatment of malnutrition, and started to screen for frailty. Clinical care was transformed in the study units; for example all sites progressed from low baseline or no screening at admission to a rate of 75%. Findings also demonstrate improvement in clinical outcomes such as a shorter length of stay. An online INPAC Implementation Toolkit was developed to promote mobilization of this knowledge. What is not known is whether or not the results can be replicated under normal circumstances (i.e., no external funding for implementation at a hospital site).

To sustain and expand on this success, a Phase 2 knowledge translation project is proposed that will involve the five original Phase 1 sites and five further hospitals as Phase 2 sites. The goal of the second phase is to see if Phase 1 sites can spread success to other units within their hospitals and if Phase 2 sites can achieve similar results across a broader group of patients.

The end product will be a sustainable model including a community of practice supported by our partner the Canadian Malnutrition Task Force, and a self-serve registry that allows sites to collect and report data to change their practice. Investigators will also confirm capacity of INPAC activities to improve clinical outcomes across diverse settings. This knowledge translation and implementation study will demonstrate the potential to transform clinical nutrition care, benefiting all pre-frail and frail older adults.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 5158
• Est. completion date: December 31, 2019
• Est. primary completion date: December 30, 2019
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Patient on the study unit

Exclusion Criteria:

• patients not on the study unit

Related Conditions & MeSH terms

• Malnutrition

Intervention

Combination Product:
• Integrated Nutrition Pathway for Acute Care
algorithm to guide care processes with respect to nutrition e.g. screening on admission, diagnosis with subjective global assessment, early treatment with medication pass of oral nutritional supplement

Locations

Country	Name	City	State
Canada	Brandon Regional Health Centre	Brandon	Manitoba
Canada	Royal Alexander Hospital	Edmonton	Alberta
Canada	Victoria General Hospital	Halifax	Nova Scotia
Canada	London Health Sciences Centre	London	Ontario
Canada	Lennox Addington County General Hospital	Napanee	Ontario
Canada	Niagara Health Systems	Niagara Falls	Ontario
Canada	Pasqua Hospital	Regina	Saskatchewan
Canada	Thunder Bay Regional Health Sciences Centre	Thunder Bay	Ontario
Canada	Concordia Hospital	Winnipeg	Manitoba

Sponsors (3)

Lead Sponsor	Collaborator
University of Waterloo	Canadian Frailty Network, Canadian Malnutrition Task Force

Country where clinical trial is conducted

Canada, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	success with implementation	rates of screening, diagnosis and treatment with medication pass per month of the study	19 months
Secondary	Adverse events while in hospital (fall, new infection etc.)		19 months
Secondary	Length of stay	Average length of stay for patients admitted to the study unit; monthly average	19 months
Secondary	Readmission rate	number of patients per month discharged and readmitted to the hospital within 30 days	19 months