Malignant Ureteral Obstruction Clinical Trial
Official title:
Comparison of the Efficacy of Silicone-covered Metallic Ureteral Stent and Double-J Stent for Malignant Ureteral Obstruction: A Prospective Randomized Controlled Trial Based on Exploratory Research
Malignant ureteral obstruction often necessitates chronic urinary diversion and is
associated with high rates of failure with traditional double-J ureteral stents. To overcome
drawbacks of the double-J stent, recently, metallic stents have been used to manage for
palliative treatment in patients with ureteral obstruction associated with end stage
malignant disease. The success rates of metallic stents have been reported to be high and
the method proved to be useful in patients with malignant ureteral obstruction. In addition,
covered metallic stents have many advantages compared with bare metallic stents, such as
lower rate of tissue invasion and higher patency rate. However, there is little
investigation about comparison of clinical efficacy between covered-metallic stents and
double-J stents in malignant ureteral obstruction.
Therefore, investigators plan to perform a prospective randomized study to compare clinical
efficacy of silicone-covered metallic ureteral stent and double-J ureteral stent in patients
with malignant ureteral obstruction.
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Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment