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Study of NGR-hTNF as Single Agent in Patients Affected by Advanced or Metastatic Malignant Pleural Mesothelioma — NGR010  

Malignant Pleural Mesothelioma Clinical Trial

Official title:
NGR010: A Phase II Study of NGR-hTNF Administered as Single Agent Every 3 Weeks or Weekly in Patients Affected by Advanced or Metastatic Malignant Pleural Mesothelioma Previously Treated With no More Than One Systemic Therapeutic Regimen

Clinical Trial Summary

The main objective of the trial is to document the progression free survival (PFS) in advanced or metastatic malignant pleural mesothelioma patients treated with NGR-hTNF as single agent.

Safety will be established by clinical and laboratory assessment according to NCI-CTC criteria.

Clinical Trial Description

This is a phase II, open-label, non-randomized study that will be conducted in patients affected by advanced or metastatic malignant pleural mesothelioma previously treated with no more than one systemic therapeutic regimen , that will be conducted using Simon's two-stage design method. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00484276
Study type Interventional
Source MolMed S.p.A.
Contact
Status Completed
Phase Phase 2
Start date May 2007
Completion date March 2013
View Details
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