Malignant Mesothelioma Clinical Trial
Official title:
Additional Circulating Markers of Angiogenesis and Disease in Mesothelioma Patients Treated on CALGB 30107
| Verified date | January 2019 |
| Source | Alliance for Clinical Trials in Oncology |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | |
| Study type | Observational |
RATIONALE: Collecting and storing samples of blood from patients with cancer to study in the
laboratory may help doctors learn more about cancer and identify biomarkers related to
cancer.
PURPOSE: This laboratory study is looking at biomarkers of angiogenesis and disease in
patients with unresectable malignant mesothelioma treated on clinical trial CALGB-30107.
| Status | Terminated |
| Enrollment | 47 |
| Est. completion date | August 2015 |
| Est. primary completion date | March 2006 |
| Accepts healthy volunteers | No |
| Gender | All |
| Age group | 18 Years and older |
| Eligibility |
DISEASE CHARACTERISTICS: - Diagnosis of malignant mesothelioma - Unresectable disease - Must have received treatment with vatalanib on protocol CALGB-30107 PATIENT CHARACTERISTICS: - Not specified PRIOR CONCURRENT THERAPY: - See Disease Characteristics |
| Country | Name | City | State |
|---|---|---|---|
| n/a | |||
| Lead Sponsor | Collaborator |
|---|---|
| Alliance for Clinical Trials in Oncology | National Cancer Institute (NCI) |
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Level of biomarkers, including thrombospondin I, vascular endothelial growth factor receptor I, fibroblast growth factor, transforming growth factor, and mesothelin (high vs low) | baseline | ||
| Secondary | Effect of biomarker expression level on overall survival | Up to 10 years |
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