NeuroPathways Intervention for Brain Tumor Patients

Status Recruiting

Clinical Trial Summary

This goal of this study is to test an information and support intervention for patients with malignant (or "high-grade") brain tumors. This study was developed to help patients cope after a brain tumor diagnosis. The main question this study aims to answer is whether this intervention (which includes access to an information guide and one-on-one coaching sessions) is feasible (i.e., possible to carry out) and acceptable (i.e., considered helpful) to patients. Participants will be asked to take part in the coaching sessions, use the guide as desired, and complete a small group of short surveys at three different points in time; some participants will be asked to share feedback via exit interviews.

Clinical Trial Description

This study will be a prospective pilot randomized controlled trial to examine the feasibility and acceptability of a novel, population-specific intervention designed to help patients with recently-diagnosed malignant brain tumors process and cope with their illness. The specific aims are to 1) refine the NeuroPathways intervention based on feedback from an open pilot study (n=up to 10) with exit interviews, 2) evaluate the feasibility and acceptability of NeuroPathways in a pilot randomized controlled trial (n=40), and 3) explore preliminary effects of the intervention on psychological, behavioral, and cognitive outcomes. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05976490
Study type	Interventional
Source	Massachusetts General Hospital
Contact	Deborah A Forst, MD
Phone	617-724-4000
Email	dforst@partners.org
Status	Recruiting
Phase	N/A
Start date	October 16, 2023
Completion date	April 10, 2026

View Details

See also
Status	Clinical Trial	Phase
Active, not recruiting	`NCT04539574` - An Investigational Scan (7T MRI) for the Imaging of Central Nervous System Tumors	N/A
Enrolling by invitation	`NCT04461002` - Evaluation of the Correlation Between Molecular Phenotype and Radiological Signature (by PET-scanner and MRI) of Incident WHO II and III Grade Gliomas.
Terminated	`NCT01902771` - Dendritic Cell Vaccine Therapy With In Situ Maturation in Pediatric Brain Tumors	Phase 1
Completed	`NCT03242824` - The Utility of 18F-DOPA-PET in the Treatment of Recurrent High-grade Glioma	Phase 2
Recruiting	`NCT04186832` - Step Count Monitoring as a Measure of Physical Activity in Patients With Newly Diagnosed Glioma Undergoing Radiation Therapy	N/A
Completed	`NCT00424554` - Low-dose Temozolomide for 2 Weeks on Brain Tumor Enzyme in Patients With Gliomas (P04602 AM1) (Completed)	Phase 2
Recruiting	`NCT05968053` - Detection of Microplastics and Nanoplastics in Neurosurgery Patients (DT-MiNi)
Not yet recruiting	`NCT04550663` - NKG2D CAR-T(KD-025) in the Treatment of Relapsed or Refractory NKG2DL+ Tumors	Phase 1
Completed	`NCT02805179` - A Study of High-Dose Chemoradiation Using Biologically-Based Target Volume Definition in Patients With Glioblastoma	Phase 2
Terminated	`NCT04556929` - Enhanced Detection in Glioma Excision	N/A
Not yet recruiting	`NCT06408428` - Glioma Intraoperative MicroElectroCorticoGraphy	N/A
Recruiting	`NCT06043232` - MMR/MSI Phenotypes in Prediction of Tumor Vaccine Benefit for Gliomas
Not yet recruiting	`NCT06043765` - Reducing Cognitive Impairment in Glioma With Repetitive Transcranial Magnetic Stimulation and Cognitive Strategy Training	N/A
Not yet recruiting	`NCT05025969` - Evaluation of the Incidence of NTRK Gene Fusion in Adult Brain Tumours
Completed	`NCT02978261` - Study of a c-Met Inhibitor PLB1001 in Patients With PTPRZ1-MET Fusion Gene Positive Recurrent High-grade Gliomas	Phase 1
Terminated	`NCT01502605` - Phase I Study of Orally Administered Aminolevulinic Acid for Resection of Malignant Astrocytomas	Phase 1
Completed	`NCT01836536` - Search for a Link Between Response to Treatment and Circulating Leucocytes in High Grade Glioma Patients	N/A
Completed	`NCT01479686` - iMRI Guided Resection in Cerebral Glioma Surgery	Phase 3
Completed	`NCT01212731` - Skull Base and Low Grade Glioma Neurocognitive Magnetic Resonance Imaging (MRI) Study
Not yet recruiting	`NCT00977327` - Comparison of Neuro-navigational Systems for Resection-Control of Brain Tumors	N/A