Frequency and Distribution of Mixed Falciparum-vivax Infections in French Guiana

Malaria Clinical Trial

— MixMal  

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02903758
• Other study ID #: mixmalaria
• Status: Completed
• Phase: N/A
• First received: September 6, 2016
• Last updated: September 13, 2016
• Start date: January 2000
• Est. completion date: December 2008

Study information

• Verified date: September 2016
• Source: Centre Hospitalier de Cayenne
• Contact: n/a
• Is FDA regulated: No
• Health authority: France: Commission nationale de l'informatique et des libertés
• Study type: Observational

Clinical Trial Summary

Malaria is still endemic in the interior of French Guiana. mixed infections by 2 or more different malaria parasites lead to complex and potentially harmfull therapeutic problems. The aim of the study was to look at malaria smears between 2000 and 2008 and determine using PCR the frequency of mixed infections, and their distribution in the terrtory of French Guiana. Overall 10.75% of 400 smears showed mixed infection with P. falciparum and P. vivax. The Maroni river where Duffy negative populations live was largely devoid of vivax infections. These results suggest that mixed infections are frequent in french guiana except on the Maroni river which leads to practical implications for clinicians facing a patient with clinical malaria.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 400
• Est. completion date: December 2008
• Est. primary completion date: January 2000
• Accepts healthy volunteers: No
• Gender: Both
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• malaria diagnosis

Exclusion Criteria:

• no malaria

Study Design

Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

• Malaria

Intervention

Other:
• cross sectional

Locations

Country	Name	City	State
France	Centre Hospitalier de Cayenne	Cayenne	French Guiana

Sponsors (2)

Lead Sponsor	Collaborator
Centre Hospitalier de Cayenne	universite de guyane

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	malaria	PCR positive for malaria parasites	At the time of diagnosis of malaria	No